DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ATL2 and mto1

DIOPT Version :9

Sequence 1:	NP_001317392.1	Gene:	ATL2 / 64225	HGNCID:	24047	Length:	584	Species:	Homo sapiens
Sequence 2:	NP_588284.1	Gene:	mto1 / 2539467	PomBaseID:	SPCC417.07c	Length:	1115	Species:	Schizosaccharomyces pombe

Alignment Length:	424	Identity:	90/424 - (21%)
Similarity:	146/424 - (34%)	Gaps:	102/424 - (24%)

- Green bases have known domain annotations that are detailed below.

Human    17 LWRRRRT---SDPSAAVNHVSSTTSLGENY-----EDDDLVNSDEVMKKPCPVQIVLAHEDDHNF 73
            |.:|.:|   .:..|..:..|.|::|.|..     |.|.|...:|..|     |::...|.
pombe   625 LQKRLQTLEEENNKAKEDSTSKTSNLLEQLKMTEAEVDSLRKENEENK-----QVIALKES---- 680

Human    74 ELDEEALEQILLQEHIRDLNIVVVSVAGAFRK---GKSFLLDFM--LRYMYNKDSQSWIGGNNEP 133
            ||.:....::||.|.|..||..:..:......   .|..|.|::  |:..:|.:..|.    |:.
pombe   681 ELVKSNDNKLLLNEQIESLNDQLSQLKTEMESVTTSKESLADYLSNLKERHNDELDSL----NKK 741

Human   134 LTGFTWRGGCERETTG-----------IQVWNEVFVIDRPNGTKVAVLLMDTQGAFDSQST---- 183
            |          ||..|           |:..|..:|..|.|...:...:|:|   ||.|.|
pombe   742 L----------REFEGILSSNSSLKSEIEERNNQYVTLRENFDSLQNAIMET---FDKQVTHCSV 793

Human   184 ---------IKDCATVFALSTMTSSVQVYNLSQNIQE---------DDLQHLQLFTEYGR----- 225
                     :||........|.....::|:..|:::|         .:.:.|:...:..|
pombe   794 NHLVQQIRKLKDENKKDQSGTDKLMKKIYHCEQSLKEKTNSLETLVSEKKELKNLLDAERRSKKA 858

Human   226 --LAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLE-GGKQFLEKRLQVKQNQHEELQNVRKHIHNC 287
              |.:|.:..:.|:.   .:...|.|.|.|...| ...|..||||   :.|.||..::.|:|...
pombe   859 IQLELENLSSQAFRR---NLSGSSSPSERSQSRELKLLQASEKRL---KEQVEERNSLIKNIVTR 917

Human   288 FSNLGCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDL 352
            |:.|.....|     |.||......:..:::......|.|           :|.|...|..|:.:
pombe   918 FTQLNTGSKP-----VNTNVEALTTISSMNQAVNMNFREL-----------DKSIQEFKRKCQSM 966

Human   353 VEYFKAYIKIYQGEELPHPKSMLQATAEANNLAA 386
            ...||..::...|......|.:.|.......|.|
pombe   967 EREFKTELRKLDGVLEARSKRLSQLEERVKLLGA 1000

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATL2	NP_001317392.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..44		8/34 (24%)
ATL2	NP_001317392.1	GBP	70..341	CDD:280433	64/316 (20%)
mto1	NP_588284.1	Cnn_1N	252..319	CDD:285263
		Fib_alpha	511..611	CDD:285864
		Mto2_bdg	1052..1101	CDD:289572
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000