| Sequence 1: | NP_001035232.1 | Gene: | SCN2A / 6326 | HGNCID: | 10588 | Length: | 2005 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001092768.1 | Gene: | Scn2a / 110876 | MGIID: | 98248 | Length: | 2006 | Species: | Mus musculus |
| Alignment Length: | 2006 | Identity: | 1966/2007 (98%) |
|---|---|---|---|
| Similarity: | 1986/2007 (99%) | Gaps: | 1/2007 (0%) |
|
Human 1 MAQSVLVPPGPDSFRFFTRESLAAIEQRIAEEKAKRPKQERKDEDDENGPKPNSDLEAGKSLPFI 65
Human 66 YGDIPPEMVSVPLEDLDPYYINKKTFIVLNKGKAISRFSATPALYILTPFNPIRKLAIKILVHSL 130
Human 131 FNMLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKILARGFCLEDFTFLRDPWNWLD 195
Human 196 FTVITFAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLS 260
Human 261 VFALIGLQLFMGNLRNKCLQWPPDNSSFEINITSFFNNSLDGNGTTFNRTVSIFNWDEYIEDKSH 325
Human 326 FYFLEGQNDALLCGNSSDAGQCPEGYICVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLY 390
Human 391 QLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATLEEAEQKEAEFQQMLEQLKK 455
Human 456 QQEEAQAAAAAASAESRDFSGAGGIGVFSESSSVASKLSSKSEKELKNRRKKKKQKEQSGEEEKN 520
Human 521 DRVRKSESEDSIRRKGFRFSLEGSRLTYEKRFSSPHQSLLSIRGSLFSPRRNSRASLFSFRGRAK 585
Human 586 DIGSENDFADDEHSTFEDNDSRRDSLFVPHRHGERRHSNVSQASRASRVLPILPMNGKMHSAVDC 650
Human 651 NGVVSLVGGPSTLTS-AGQLLPEGTTTETEIRKRRSSSYHVSMDLLEDPTSRQRAMSIASILTNT 714
Human 715 MEELEESRQKCPPCWYKFANMCLIWDCCKPWLKVKHLVNLVVMDPFVDLAITICIVLNTLFMAME 779
Human 780 HYPMTEQFSSVLSVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVSLSLMELGLANVE 844
Human 845 GLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKE 909
Human 910 CVCKISNDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLTVFMMVMVIGNLVV 974
Human 975 LNLFLALLLSSFSSDNLAATDDDNEMNNLQIAVGRMQKGIDFVKRKIREFIQKAFVRKQKALDEI 1039
Human 1040 KPLEDLNNKKDSCISNHTTIEIGKDLNYLKDGNGTTSGIGSSVEKYVVDESDYMSFINNPSLTVT 1104
Human 1105 VPIAVGESDFENLNTEEFSSESDMEESKEKLNATSSSEGSTVDIGAPAEGEQPEVEPEESLEPEA 1169
Human 1170 CFTEDCVRKFKCCQISIEEGKGKLWWNLRKTCYKIVEHNWFETFIVFMILLSSGALAFEDIYIEQ 1234
Human 1235 RKTIKTMLEYADKVFTYIFILEMLLKWVAYGFQVYFTNAWCWLDFLIVDVSLVSLTANALGYSEL 1299
Human 1300 GAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFY 1364
Human 1365 HCINYTTGEMFDVSVVNNYSECKALIESNQTARWKNVKVNFDNVGLGYLSLLQVATFKGWMDIMY 1429
Human 1430 AAVDSRNVELQPKYEDNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQ 1494
Human 1495 KKYYNAMKKLGSKKPQKPIPRPANKFQGMVFDFVTKQVFDISIMILICLNMVTMMVETDDQSQEM 1559
Human 1560 TNILYWINLVFIVLFTGECVLKLISLRYYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTL 1624
Human 1625 FRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREV 1689
Human 1690 GIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSGPPDCDPDKDHPGSSVKGDCGNPSVGIF 1754
Human 1755 FFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFIEFAKLS 1819
Human 1820 DFADALDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEERFM 1884
Human 1885 ASNPSKVSYEPITTTLKRKQEEVSAIIIQRAYRRYLLKQKVKKVSSIYKKDKGKECDGTPIKEDT 1949
Human 1950 LIDKLNENSTPEKTDMTPSTTSPPSYDSVTKPEKEKFEKDKSEKEDKGKDIRESKK 2005 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| SCN2A | NP_001035232.1 | I. {ECO:0000305} | 111..456 | 337/345 (98%) | |
| Ion_trans | 150..435 | CDD:278921 | 278/285 (98%) | ||
| Na_trans_cytopl | 514..630 | CDD:288761 | 108/116 (93%) | ||
| II. {ECO:0000305} | 741..1013 | 271/272 (100%) | |||
| Ion_trans | 776..971 | CDD:278921 | 195/195 (100%) | ||
| Na_trans_assoc | 997..1203 | CDD:284034 | 205/206 (100%) | ||
| III. {ECO:0000305} | 1190..1504 | 312/314 (99%) | |||
| Ion_trans | 1225..1482 | CDD:278921 | 255/257 (99%) | ||
| Na_channel_gate | 1474..1526 | CDD:240441 | 52/52 (100%) | ||
| IV. {ECO:0000305} | 1513..1811 | 296/298 (99%) | |||
| Ion_trans | 1548..1786 | CDD:278921 | 236/238 (99%) | ||
| GPHH | 1798..1853 | CDD:293510 | 53/55 (96%) | ||
| Scn2a | NP_001092768.1 | I. {ECO:0000250|UniProtKB:P04775} | 111..456 | 337/345 (98%) | |
| Ion_trans | 128..435 | CDD:334124 | 299/307 (97%) | ||
| Na_trans_cytopl | 516..700 | CDD:338179 | 171/184 (93%) | ||
| II. {ECO:0000250|UniProtKB:P04775} | 742..1014 | 271/272 (100%) | |||
| Ion_trans | 759..972 | CDD:334124 | 213/213 (100%) | ||
| Na_trans_assoc | 998..1204 | CDD:336429 | 205/206 (100%) | ||
| III. {ECO:0000250|UniProtKB:P04775} | 1191..1505 | 312/314 (99%) | |||
| Ion_trans | 1208..1483 | CDD:334124 | 273/275 (99%) | ||
| Na_channel_gate | 1475..1527 | CDD:240441 | 52/52 (100%) | ||
| IV. {ECO:0000250|UniProtKB:P04775} | 1514..1812 | 296/298 (99%) | |||
| Ion_trans | 1532..1787 | CDD:334124 | 253/255 (99%) | ||
| GPHH | 1791..1854 | CDD:339854 | 61/63 (97%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | C370013751 | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| HGNC | 1 | 1.500 | ||||
| Hieranoid | 1 | 1.000 | ||||
| Homologene | 1 | 1.000 | H75001 | |||
| Inparanoid | 1 | 1.050 | 3923 | 1.000 | Inparanoid score | I278 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | ||||
| OrthoDB | 1 | 1.010 | D37221at33208 | |||
| OrthoFinder | 1 | 1.000 | FOG0000322 | |||
| OrthoInspector | 1 | 1.000 | T2446743 | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | LDO | PTHR10037 | ||
| Phylome | 1 | 0.910 | 0.800 | Consistency score | ||
| RoundUp | 1 | 1.030 | avgDist | Average_Evolutionary_Distance | R9280 | |
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 12 | 12.540 | |||||