Protein Alignment ACTB and Arp1

DIOPT Version :10

• Sequence 1: NP_001092.1
• Gene: ACTB / 60
• HGNCID: 132
• Length: 375
• Species: Homo sapiens
• Sequence 2: NP_524331.2
• Gene: Arp1 / 41566
• FlyBaseID: FBgn0011745
• Length: 376
• Species: Drosophila melanogaster
• Alignment Length: 370
• Identity: 202/370 - (54%)
• Similarity: 273/370 - (73%)
• Gaps: 7/370 - (1%)

Human     8 LVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIE 72
            :|:|||||:.||||||:..|:..||:.:|||:|..||.|..:.|.:||.:|:..||:|:::||:|
  Fly    12 VVIDNGSGVIKAGFAGEHIPKCRFPNYIGRPKHVRVMAGALEGDIFVGPKAEEHRGLLSIRYPME 76

Human    73 HGIVTNWDDMEKIWHHTFYNE-LRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAI 136
            |||||:|:|||:||.:.:..| |....|:||||||||||||:.||||..:..||..|.||::|::
  Fly    77 HGIVTDWNDMERIWSYIYSKEQLATFTEDHPVLLTEAPLNPRRNREKAAEFFFEGINAPALFVSM 141

Human   137 QAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFT 201
            ||||||||:||.||:|:||||||||.||||||:|:||:|:|:|:||||:|.||..::...|::|.
  Fly   142 QAVLSLYATGRVTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVTRYLKTLIRREGFNFR 206

Human   202 TTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEK-SYELPDGQVITIGNERFRCPEALFQPS 265
            :|||.||||.||||:||:|.:.::|     .:...|| :|:||||::..||..|||.||.||:|.
  Fly   207 STAEFEIVRSIKEKVCYLATNPQKE-----ETVETEKFAYKLPDGKIFEIGPARFRAPEVLFRPD 266

Human   266 FLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKII 330
            .||.|..|||:....||.|.|:|:||.||.|.|||||:|::.|..||:..|:...:...:||:|.
  Fly   267 LLGEECEGIHDVLMYSIEKSDMDLRKMLYQNIVLSGGSTLFKGFGDRLLSELKKHSAKDLKIRIA 331

Human   331 APPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 375
            ||.||.||.|:||||||||.||::|||||:||:|.|...||||.|
  Fly   332 APQERLYSTWMGGSILASLDTFKKMWISKREYEEEGQKAVHRKTF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACTB	NP_001092.1	ASKHA_NBD_actin	6..370	CDD:466823	197/363 (54%)
Arp1	NP_524331.2	ASKHA_NBD_Arp1	9..375	CDD:466820	200/367 (54%)