Protein Alignment ACTB and Arp53D

DIOPT Version :10

• Sequence 1: NP_001092.1
• Gene: ACTB / 60
• HGNCID: 132
• Length: 375
• Species: Homo sapiens
• Sequence 2: NP_477037.2
• Gene: Arp53D / 36879
• FlyBaseID: FBgn0011743
• Length: 411
• Species: Drosophila melanogaster
• Alignment Length: 370
• Identity: 241/370 - (65%)
• Similarity: 294/370 - (79%)
• Gaps: 5/370 - (1%)

Human     6 AALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYP 70
            ||:|:|||||:|||||:.:|.||||||||||||||..|::.....||.:|:.|..||||||||||
  Fly    47 AAVVIDNGSGVCKAGFSPEDTPRAVFPSIVGRPRHLNVLLDSVIGDSVIGEAAARKRGILTLKYP 111

Human    71 IEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVA 135
            ||||:|.|||:||.:|.|| |..||..|.:.|.||||||||||.||||||:||||.|..||.|||
  Fly   112 IEHGMVKNWDEMEMVWQHT-YELLRADPMDLPALLTEAPLNPKKNREKMTEIMFEHFQVPAFYVA 175

Human   136 IQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSF 200
            :||||||||:|||.|||:|||||||||||||||:|||||.:|:|||||||||||.|:|.|||.:.
  Fly   176 VQAVLSLYATGRTVGIVVDSGDGVTHTVPIYEGFALPHACVRVDLAGRDLTDYLCKLLLERGVTM 240

Human   201 TTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPS 265
            .|:|||||||:||||||||::::.:||    ......::|||||||.|.:|.|||||||||||||
  Fly   241 GTSAEREIVREIKEKLCYVSMNYAKEM----DLHGKVETYELPDGQKIVLGCERFRCPEALFQPS 301

Human   266 FLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKII 330
            .||.|..||||.|.:||..||:|:|||:|||.||||||||:..|..|..:::|.:||.:::||:.
  Fly   302 LLGQEVMGIHEATHHSITNCDMDLRKDMYANIVLSGGTTMFRNIEHRFLQDLTEMAPPSIRIKVN 366

Human   331 APPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 375
            |.|:|::|||.|||:||||::||.|||...||:|.|.:|||||||
  Fly   367 ASPDRRFSVWTGGSVLASLTSFQNMWIDSLEYEEVGSAIVHRKCF 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACTB	NP_001092.1	ASKHA_NBD_actin	6..370	CDD:466823	234/363 (64%)
Arp53D	NP_477037.2	ASKHA_ATPase-like	47..406	CDD:483947	234/363 (64%)