Protein Alignment Zwilch and zwl-1

DIOPT Version :10

• Sequence 1: NP_733421.1
• Gene: Zwilch / 59247
• FlyBaseID: FBgn0061476
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001249150.1
• Gene: zwl-1 / 171798
• WormBaseID: WBGene00021460
• Length: 630
• Species: Caenorhabditis elegans
• Alignment Length: 476
• Identity: 88/476 - (18%)
• Similarity: 163/476 - (34%)
• Gaps: 130/476 - (27%)

  Fly    38 GAAEAGKKIVLVFKEDRNGAVARLRTTPTRAAPKKEGSADLDLT--GSPLKDDCLV------DAI 94
            ||.:|.||  ::||:              :..|.::...|.:..  |.||....|.      ..:
 Worm    76 GAGKAEKK--MIFKK--------------KIEPMEDSFEDKENVNEGGPLMTSFLTLEKLRKGMV 124

  Fly    95 ADLSI-----DLQLDHSNPWKLEEEYQRGIPVDKARSIVCSEFLQLAEGLGSVWFLCDGSDL--- 151
            .|:.|     :.....:||..|.:    |:.:.:...:.|||....:.....||.....|..
 Worm   125 GDVEIIGYECETSFFDANPIPLSD----GVSLQRYIRLNCSEHFSPSISTLPVWISTTSSKFPSI 185

  Fly   152 -----GQT-QLLQY--------EFNPTHFSR---------GILSYQGVRPAYLVTSQALVRHHGK 193
                 |:| :.:|:        .||..:..|         |.......|..| ...:.:...:..
 Worm   186 CWLAAGRTNRNVQFAAATRVLGHFNNENSERVVKQLNQACGTSQLNKYRAVY-EEIRKIATENRP 249

  Fly   194 TPDETLIENSYQVNPHMRLRCSWTSSAALPLLV---NLNDCDVAL-----NHTFRVGDCGPLTQD 250
            .|.|..|:            ..|::.:.|.||.   |..||.:.:     :..|.|.|      :
 Worm   250 APGEVTID------------VRWSTKSTLVLLEHPDNAADCTIKIDLGWGDKRFFVDD------E 296

  Fly   251 FMNQLRILVYIREDIVSYHTDVKQGVSRDPTYRCGSGIDMDELRESINQTMTDVSGLIGRYSISN 315
            ...||..::.:        .||......:..:......:.|:|.:.:: .:.:.|.......:||
 Worm   297 IFEQLFFVLNL--------ADVLANPDNEVIFPMAPPANFDDLVQEMD-ALVEASSREDNVFVSN 352

  Fly   316 AEFDIEDVVQRAKVRQLTDLTDKLWELLKCCHSYKDLKIAFSMLFQCAARCNIVN--TPTNKNRL 378
            ..|            :..|:|||:|.:::.|:..|.:.:.|....|..|...|.:  ...||:.|
 Worm   353 ENF------------RGGDITDKVWNIVRKCNDVKQVTLLFRNFLQALAYGKIKSHAQERNKSHL 405

  Fly   379 AKIITELANRRLAMPCLSGAEPLELLLEIGLEKLYK---------------DYEFIYTESKMCST 428
            |.:|....:....:|.|.....:::::|||:|.|.:               :.|||.   :.|..
 Worm   406 ASLIRISKSSEFKIPVLERLSTIDMMMEIGVESLRRRVIDIFSSQLLYPSDELEFIL---QTCEN 467

  Fly   429 NLLKDDSSGASMDDGSPQNLP 449
            :|   .:...:|:..:...||
 Worm   468 DL---PAGNGAMNSAAISLLP 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zwilch	NP_733421.1	Zwilch	29..627	CDD:401684	88/476 (18%)
zwl-1	NP_001249150.1	Zwilch	27..623	CDD:401684	88/476 (18%)