Protein Alignment MCU and Mcub

DIOPT Version :10

• Sequence 1: NP_001246647.1
• Gene: MCU / 59223
• FlyBaseID: FBgn0042185
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_080055.3
• Gene: Mcub / 66815
• MGIID: 1914065
• Length: 336
• Species: Mus musculus
• Alignment Length: 270
• Identity: 93/270 - (34%)
• Similarity: 163/270 - (60%)
• Gaps: 0/270 - (0%)

  Fly   163 EDIYVEYVNGMPHMTVRLPSRNELCQFALKPISHNVGDLLAMLRAEDRGIDRAAVINKHGVRIAS 227
            ::|.|.|.:|:|.:|:.||||.|.|||.:||:...||..|..|:.||:||..||:|...|..|.:
Mouse    58 DEITVTYKHGLPLVTLTLPSRKERCQFVVKPMLSTVGSFLQDLQNEDKGIKTAAIITADGSEIPA 122

  Fly   228 SCTIESLLDDSFSIQINNRTLDVNPPKRDKVTLESMDKVGDVRKVIAQLYEAFNVGEYQLEKSNQ 292
            |..:::||...|.:.||....|:...|:::.:.|.|.::.:.:.::.:|:...::.|.|..:...
Mouse   123 STLMDTLLMTDFKLIINKLRYDIRCHKKEEPSGEHMTELENTKSLVHRLFTILHLEEIQKRRERH 187

  Fly   293 LAKELETLRYELEPLEEKKLELSKKAARRTNFMTWMGLGLMSVQFGILARLTWWEYSWDIMEPVT 357
            |..:::.|:.:|.|||:.|..:..::...|:.:.|.||.|:|||.|.||.||||.||||||||||
Mouse   188 LMAKIDHLQEQLRPLEQVKAAIEARSEANTSGLLWAGLALLSVQGGALAWLTWWVYSWDIMEPVT 252

  Fly   358 YFVTYGTTMAMYAYYCVTKREYMMEDVKNREFSLSLYRNAKKVQFDVEHYNELKRKSAELEYNLR 422
            :|:::..::..:||:.:|::.|....:::|:|....::.:::..||||.||:||...||...:|.
Mouse   253 FFLSFANSIVFFAYFIITRQNYTYSSLRSRQFLQFFHKKSQRRCFDVEQYNKLKEDLAEATESLE 317

  Fly   423 RINDPLNMQL 432
            .:...|.:::
Mouse   318 SVRRSLRLRI 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MCU	NP_001246647.1	MCU	208..410	CDD:461389	67/201 (33%)
Mcub	NP_080055.3	MCU	103..305	CDD:461389	67/201 (33%)