DRSC/TRiP Functional Genomics Resources

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Protein Alignment MCU and MCU

DIOPT Version :10

Sequence 1:NP_001246647.1 Gene:MCU / 59223 FlyBaseID:FBgn0042185 Length:457 Species:Drosophila melanogaster
Sequence 2:XP_316356.3 Gene:MCU / 1276945 VectorBaseID:AGAMI1_009246 Length:446 Species:Anopheles gambiae


Alignment Length:436 Identity:189/436 - (43%)
Similarity:272/436 - (62%) Gaps:41/436 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 LALRLAPGTTFALHLRPCHEL----QQHRSFASTAED-GETDKHKKPT------TGGHSSSQHVD 80
            :|:..|.|...:| ||.||.|    :.||...:.... ......:|.|      :..:|::..|.
Mosquito     1 MAVPKAAGNGASL-LRSCHMLLARAEGHRGGGALLNSLARNQSWRKETALIVCASRRYSTTATVA 64

  Fly    81 EQAGCDDKIREKKSKSNHCLVKYRKGDQETEKGTNPCGAQEFKESNSFAGTQVHSLKKRIKNRKI 145
            ...||.::...:.::....::          :|...|.|.....|||.....    ::.|.:...
Mosquito    65 ASGGCSNRGPSRSTRKPSIII----------EGGVVCRAYSSTSSNSGGAVS----RRHISSSST 115

  Fly   146 KKKLILNRKKKKKKTCN--EDIYVEYVNGMPHMTVRLPSRNELCQFALKPISHNVGDLLAMLRAE 208
            ..    :.......|.|  |::.|.|..|:||:||.||||||.|||.|:|::|.|||.|.||:.|
Mosquito   116 SS----SSSASSTNTSNAPEEVSVRYYRGLPHVTVPLPSRNERCQFTLRPVTHCVGDFLDMLKVE 176

  Fly   209 DRGIDRAAVINKHGVRIASSCTIESLLDDSFSIQINNRTLDVNPPKRDKVTLESMDKVGDVRKVI 273
            ||||||||::|:.|||||::|:||:|:||.|.:.:|:|...|.||||:|:|.|.:.::|||:.::
Mosquito   177 DRGIDRAAILNREGVRIAAACSIENLMDDEFWLHLNDRQYYVKPPKREKITSEEITRLGDVQALV 241

  Fly   274 AQLYEAFNVGEYQLEKSNQLAKELETLRYELEPLEEKKLELSKKAARRTNFMTWMGLGLMSVQFG 338
            ||||||.:|||:|::|..:|..:||.|..:|.|||.||.||.:||||:||.:||:||||||||||
Mosquito   242 AQLYEALHVGEHQVQKERELNGKLEQLNEKLGPLEAKKNELDQKAARKTNALTWVGLGLMSVQFG 306

  Fly   339 ILARLTWWEYSWDIMEPVTYFVTYGTTMAMYAYYCVTKREYMMEDVKNREFSLSLYRNAKKVQFD 403
            :|||||||||||||||||||||||||.||.|||:.:||:||::.|||:|:..::|::.|||...:
Mosquito   307 VLARLTWWEYSWDIMEPVTYFVTYGTAMAAYAYFVLTKQEYLLPDVKDRQHLITLHKAAKKAGVN 371

  Fly   404 VEHYNELKRKSAELEYNLRRINDPLNMQLPSHLVRTQENTPPTLTE 449
            :..||::||:.||:|::|||:.|||.|.||:         ||..|:
Mosquito   372 LAEYNDIKRQIAEIEHDLRRLRDPLYMHLPA---------PPPKTK 408

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MCUNP_001246647.1 MCU 208..410 CDD:461389 120/201 (60%)
MCUXP_316356.3 MCU 176..376 CDD:461389 121/199 (61%)

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