Protein Alignment MCU and mcub

DIOPT Version :10

• Sequence 1: NP_001246647.1
• Gene: MCU / 59223
• FlyBaseID: FBgn0042185
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_001120048.1
• Gene: mcub / 100145024
• XenbaseID: XB-GENE-5744060
• Length: 319
• Species: Xenopus tropicalis
• Alignment Length: 281
• Identity: 120/281 - (42%)
• Similarity: 181/281 - (64%)
• Gaps: 2/281 - (0%)

  Fly   162 NEDIYVEYVNGMPHMTVRLPSRNELCQFALKPISHNVGDLLAMLRAEDRGIDRAAVINKHGVRIA 226
            :.|:.|:|.:|:|.:|:.||||||.|||.:||::..:|..|..::.||||||..|..:....:.:
 Frog    40 SSDVTVQYSHGLPVITLTLPSRNERCQFTIKPLTTTLGTFLTDIKKEDRGIDVIAATSTDDTKFS 104

  Fly   227 SSCTIESLLDDSFSIQINNRTLDVNPPKRDKVTLESMDKVGDVRKVIAQLYEAFNVGEYQLEKSN 291
            :|..::.||.:.|.:.|||.|..|.||.|||...:...::..::.::.:||.|.:..||||.|..
 Frog   105 NSTLMDVLLMNDFKLVINNSTYHVQPPSRDKPCPQDSSEMDTIKTLVHRLYAALHQEEYQLNKEQ 169

  Fly   292 QLAKELETLRYELEPLEE-KKLELSKKAARRTNFMTWMGLGLMSVQFGILARLTWWEYSWDIMEP 355
            :|.|.|::|:.:|:|||: |.:.|||..|:.|..| |:||.|||.|.|.||.||||.||||||||
 Frog   170 ELLKRLDSLKEQLQPLEQMKSMILSKSDAKTTRLM-WIGLALMSTQGGALAWLTWWVYSWDIMEP 233

  Fly   356 VTYFVTYGTTMAMYAYYCVTKREYMMEDVKNREFSLSLYRNAKKVQFDVEHYNELKRKSAELEYN 420
            ||||:|||:.:|.|||:.:||::|:...::.|:.....|:.||..:|||..||.|:.:.||.|.:
 Frog   234 VTYFITYGSAIAFYAYFVLTKQDYVYPAIRERQLLNYFYKRAKTQRFDVNEYNRLQEEFAETEES 298

  Fly   421 LRRINDPLNMQLPSHLVRTQE 441
            |||:.:||.:.||...:..:|
 Frog   299 LRRLQNPLRLGLPIEQLNEKE 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MCU	NP_001246647.1	MCU	208..410	CDD:461389	89/202 (44%)
mcub	NP_001120048.1	MCU	86..288	CDD:461389	89/202 (44%)