Protein Alignment Capr and Caprin2

DIOPT Version :10

• Sequence 1: NP_652671.1
• Gene: Capr / 59172
• FlyBaseID: FBgn0042134
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_001387999.1
• Gene: Caprin2 / 686779
• RGDID: 1593683
• Length: 1029
• Species: Rattus norvegicus
• Alignment Length: 926
• Identity: 202/926 - (21%)
• Similarity: 321/926 - (34%)
• Gaps: 310/926 - (33%)

  Fly    75 SQTDLASSNNNGNAAKSKANAVSAAAVVPEPYNP-LKQLLVTIEHKIRNLEKRKTKLESYRAIQS 138
            ||.:......|..|.....:.:|:||...:.|.. :...|:.::|||||:||:|.|||.|:....
  Rat     6 SQVNHTQQGENQRALSPLQSTLSSAASPSQAYETYIDNGLICLKHKIRNIEKKKLKLEDYKDRLK 70

  Fly   139 SGKELSGDQASAVAKYDAVLANLEFARELAKHIQQQSKEAEKEQKKQARKDNLAKTIAETAKIRE 203
            :|::|:.||..||.||:.||.|||||:||.|.....|::..|.|||..|::::.|..||..|:|.
  Rat    71 NGEQLNPDQLEAVEKYEEVLHNLEFAKELQKTFSALSQDLLKAQKKAQRREHMLKLEAEKKKLRT 135

  Fly   204 VLIIQNVLNCFNDDQVRSDFLNGENGAKKLENTELELLEKFFIETQTRRPETADDVSFIATAQKS 268
            :|.||.||.....:.|:.||..|.|||..|.:.||:.|.||   ::...||..:.:|.....::|
  Rat   136 ILQIQYVLQNLTQEHVQKDFKGGLNGAMYLPSKELDYLIKF---SKLTCPERNESLSVEDQMEQS 197

  Fly   269 AELFYSTINARPKSFGEVSFEKLRSLFQQIQDSGYLDKYYLVPLAENAVANSTDSGTGSGDGESG 333
            :..|:..:....|:....:::.::.|..::..|||.:.   ||:..|
  Rat   198 SLYFWDLLEGSEKAVVGTTYKHVKDLLSKLLHSGYFES---VPVLRN------------------ 241

  Fly   334 DLLNDGSGELDAELPSEPSARNSL--------EEGLDKLHLGVQAEL------------------ 372
                  |.|...|:..:...|..|        .|.|.:|   ||.|:
  Rat   242 ------SKEKTEEMLMQSEKRKQLLKTESIKESESLKEL---VQPEIQPQEFLNRRYMTEVNFSR 297

  Fly   373 ---DQHQSYQQQQERPSHLL-------EP------------------------------QHQRAP 397
               ::.||::....|...||       ||                              |.:..|
  Rat   298 KQENEEQSWEADYARKPGLLKCWNTLPEPDGQEKKKESVESWESSLKSQEVSKPVVSFEQEKLRP 362

  Fly   398 SLEHQQNSMVQQVS-TQVYQAAPQA-----GGTTTPVHVLYAP-----APPAQQQPQQPPPHPHQ 451
            :|:.:|.   ||:| ..|.|..|::     |......:|...|     .|..:|.|::.||.
  Rat   363 TLQEEQK---QQISMAPVSQWKPESPKSKVGSPQEEQNVQETPKPWVVQPQKEQDPKKLPPG--- 421

  Fly   452 LLSSPVNLQALQTGT---AAPPAQQQ---QP-----------HPTH------------------- 480
              |..|::|:.|:|:   ..|..::|   ||           :..|
  Rat   422 --SWAVSVQSEQSGSRSWTTPVCREQASVQPGTPVSWENNAENQKHSLVPQSQISLKSWGAASAG 484

  Fly   481 FAPNVRA------VEQNYFKQPPQHPQGPGIQAPQTPQQQQ---------------FMQHS---- 520
            ..||.:.      ||.....:|...|.......|:.|..::               |||.|
  Rat   485 LLPNDKVPPRKLNVEPKDVPKPMPQPIDSSSPFPKDPALRKEKLQDLMTQIQGTCNFMQESVLDV 549

  Fly   521 ---------------RPLAEVLG----TGRFHFLQD-------------------------SEL- 540
                           .|::.|..    :.:..|||:                         ||.
  Rat   550 DTPSSAIPSSQPPSASPVSAVSAEQNLSNQSDFLQEPSKASSPVTCSSNACLVTTDQASLGSETE 614

  Fly   541 ----DNPEALAPP-----------PPTNQGLVFEQQPQQPNHV---EEPTQAILTLTFTNQSFPS 587
                :.||.:|||           ||.::|  |:..|...:..   ..|.||:.|:...|...|.
  Rat   615 FMTSETPEMVAPPCKPASALASPNPPLSKG--FQLPPASGSSAAISTAPFQAMQTVFNVNAPLPP 677

  Fly   588 QQPQPQQQGP--------------QQQQQLFSPVLIHEQRQQPPQQ------------------- 619
            ::.|..::.|              |...|...|.:..||..|||:.
  Rat   678 RKEQAMKESPYSSGYSQSFTSSSTQTVSQCQLPAVHVEQTTQPPETAAGYHPDGTVQVSNGSLAF 742

  Fly   620 QPQPMLIMPRLPTQQPQQPAPQGIGMQAGDVTSG----------FSYE---------NAVVSYEQ 665
            .|.|..:.||     |.||.....|...|....|          .||:         :|......
  Rat   743 YPAPTSMFPR-----PAQPFISSRGALRGCSRGGRLLMNPYRSPGSYKGFDSYRGLPSASSGTYS 802

  Fly   666 QIQQQLKQQQQQQQQQQQNLQQLDEPSSVNS---SSSVGAGGDVENNEWHARNNDTNAAATAALT 727
            |:|.|.::.......|:.|.||..:.|..:|   ::|.....|........|:::|..:..:.:
  Rat   803 QLQLQAREYPGTPYSQRDNFQQCYKRSGTSSGLQANSRAGWSDSSQVSSPERDSETFNSGDSGV- 866

  Fly   728 NVLKGETTQATPPAPP 743
                |::...||...|
  Rat   867 ----GDSRSMTPVDVP 878

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Capr	NP_652671.1	PRK12704	<109..>199	CDD:237177	40/89 (45%)
		Caprin-1_dimer	187..305	CDD:436391	34/117 (29%)
		PRK11634	<802..858	CDD:236941
Caprin2	NP_001387999.1	PRK03918	<48..>366	CDD:235175	93/350 (27%)
		Caprin-1_dimer	119..234	CDD:436391	34/117 (29%)
		Caprin-1_C	528..837	CDD:463522	59/315 (19%)
		C1q	901..1026	CDD:395310