DRSC/TRiP Functional Genomics Resources

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Protein Alignment Capr and caprin2

DIOPT Version :10

Sequence 1:NP_652671.1 Gene:Capr / 59172 FlyBaseID:FBgn0042134 Length:961 Species:Drosophila melanogaster
Sequence 2:XP_068075680.1 Gene:caprin2 / 407729 ZFINID:ZDB-GENE-040812-2 Length:934 Species:Danio rerio


Alignment Length:911 Identity:180/911 - (19%)
Similarity:326/911 - (35%) Gaps:206/911 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 SNSSAAATADGSQTDLASSNNNGNAAKSKANAVSAAAVV---------PEPYNPLKQLLVTIEHK 119
            |.|....|...|:..:...:..|:........:||..:.         .|.|  ::..|:.::||
Zfish    11 SPSRTLETLTPSELTVEKDDGQGSPKPESPRMLSALQLALSSTTVYCGYEKY--IEDGLICLKHK 73

  Fly   120 IRNLEKRKTKLESYRAIQSSGKELSGDQASAVAKYDAVLANLEFARELAKHIQQQSKEAEKEQKK 184
            |||:||:|.|||.|......|::|:.||..||.|||.|:.||:||:||.|.|...:::..|.|:|
Zfish    74 IRNIEKKKLKLERYSDKLKKGEKLNEDQLEAVGKYDEVVHNLKFAKELQKTIGSLTQDLLKAQRK 138

  Fly   185 QARKDNLAKTIAETAKIREVLIIQNVLNCFNDDQVRSDFLNGENGAKKLENTELELLEKFFIETQ 249
            ..|::...||..|.:::..:|.:|.||:....:.||.:|.|....:..:...::|.|........
Zfish   139 AVRQEKQMKTDEEKSRLSLMLQVQYVLHSLQREDVRKNFCNTRQYSCYMSTQDMEGLMDLASLVG 203

  Fly   250 TRRPETADDVSFIATAQKSAELFYSTINARPKSFGEVSFEKLRSLFQQIQDSGYLDKYYLVPLAE 314
            .:|..:   :|.....:::|.:::..:....|.....:::.::....::.|||:.|.   :||.:
Zfish   204 CKRDYS---ISLEDQMRRAAIVYWELLEGNEKPVAGSTYKHMKEKLLRLVDSGFFDN---IPLPK 262

  Fly   315 NAVANSTDSGTGSGDGESGDLLNDGSGELDAELPSEPSARNSLEEGLDKLHLGVQAELDQHQSYQ 379
            :.....|::                   :..:..|.||...:|.: |....:..:..|::....:
Zfish   263 SDSQEKTET-------------------IKPDSQSRPSGLTTLVK-LSSNEVPSKEFLNRRYMPE 307

  Fly   380 QQQERPSHLLEPQHQRAPSLEHQQNSMVQQVSTQVYQAAPQAGGTTTPVHVLYAPAPPAQQQPQQ 444
            ..:.|......|::.:...|     :|.::.....::....|.             |||..|...
Zfish   308 TDERRRGETASPRNWKEDFL-----AMKEREPPDSWEMEELAD-------------PPASSQSPI 354

  Fly   445 PPPHPHQLLSSPVNLQALQTGTAAPPAQQQQPHPTHFAPNVR-AVEQNYFKQPPQHPQGPGIQAP 508
            ..|........|..:..::..|..|..::|:......:.::. |||  .|..|...|:.| :|..
Zfish   355 QKPWKGAAGLIPKTVDIVKRSTTDPKEKRQRKKAEQDSKSMPVAVE--VFSSPSPLPKDP-VQRR 416

  Fly   509 QTPQQQQFMQHSRPLAEVLGTGRFHFLQDSELDNPEALAPPPPTNQGLVFEQQPQQPNHVEEPTQ 573
            |  |.:..|...        :|.|.|:|:|.||...:     |.|                    
Zfish   417 Q--QLETLMDQI--------SGSFSFMQESLLDGESS-----PVN-------------------- 446

  Fly   574 AILTLTFTNQSFPSQQPQPQQQGPQQQQQLF---SPVLIHEQRQQPPQQQPQPMLIMPRLPTQQP 635
                 |.|.:.    :|.|....|..|::|.   |.:|       |..|:..|:.|:..      
Zfish   447 -----TQTKRC----RPSPGSSTPIVQRELTKSPSDIL-------PSSQRSTPLRILLS------ 489

  Fly   636 QQPAPQGIGMQAGDVTSGFSYENAVVSYEQQIQQQLKQQQQQQQQQQQNLQQLDEPSSVNSSSSV 700
                    |...|.:::|   :.::...:.::..:.|.::|        .:..:.|......||:
Zfish   490 --------GEGKGCLSNG---DRSINGSDLELHSEDKPRKQ--------AEGFNSPPLYRRGSSI 535

  Fly   701 GAGGDVENNEWHARNNDTNAAATAALTNVLKGETTQATPPAPPTKWS-----------SEMNAMS 754
            ...         ..|..|..|....|.|.:....:..|...||::.|           |..|.:.
Zfish   536 SVS---------LENQSTVQAGRQMLCNGVSSSGSAQTFSTPPSRRSISAENPFHNIHSVFNVIG 591

  Fly   755 -----SAASNGSSNTSHKQEWATPRDHSTGGGNSGYADNNESNNHWNNSQGDGRRNSGNYQ---- 810
                 .|..:|.|.:.|       |..::...:|....:.::....|..:.| .:..|.|.    
Zfish   592 ESSGMKADESGFSESIH-------RSFTSAKTSSVTTASTQTPPELNPPEED-LQIEGQYPLECA 648

  Fly   811 -RRGGDRDNRDRDQGGRGDERRNGGDRGNYRSRQYGNSSNTNGRNSGNSSGVYFRNNESGNGGGN 874
             ..||...:....:.|:....| |..||..|:          ||..|:|    ||:.....||.:
Zfish   649 VSAGGPVFSSSHSRVGQSCYSR-GAVRGMMRA----------GRALGHS----FRSPGGYRGGYD 698

  Fly   875 NYYQNGGGGGGTYNKESRYESSGGGGGSYRGQRGGNQQRNVNGSYGGGRPMGDRGRGGAGNQGGG 939
            .|..|....||::..::..|.:   ...|..:..|.||.            ..||.|.|..:...
Zfish   699 AYRVNVRSPGGSFMSQTHREPA---SALYMARENGYQQN------------FKRGAGTATQRSSA 748

  Fly   940 G 940
            |
Zfish   749 G 749

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CaprNP_652671.1 PRK12704 <109..>199 CDD:237177 38/89 (43%)
Caprin-1_dimer 187..305 CDD:436391 21/117 (18%)
PRK11634 <802..858 CDD:236941 13/60 (22%)
caprin2XP_068075680.1 Caprin-1_dimer 141..256 CDD:436391 21/117 (18%)
Caprin-1_C 419..746 CDD:463522 81/447 (18%)
C1q 806..931 CDD:395310
Blue background indicates that the domain is not in the aligned region.

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