Protein Alignment PTK7 and CG13506

DIOPT Version :10

• Sequence 1: NP_001257327.1
• Gene: PTK7 / 5754
• HGNCID: 9618
• Length: 1078
• Species: Homo sapiens
• Sequence 2: NP_611666.2
• Gene: CG13506 / 37556
• FlyBaseID: FBgn0034723
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 294
• Identity: 71/294 - (24%)
• Similarity: 115/294 - (39%)
• Gaps: 41/294 - (13%)

Human   433 EGKPG---YLDC------LTQATPKPTVVWYRNQMLISE-----DSRFEVFKNGTLRINSVEVYD 483
            |.|||   .|:|      |:.|     ||||:|:::|:.     ..|.:...|.::.:.:|...|
  Fly    80 EAKPGDDVILNCDARNFQLSNA-----VVWYKNRIIIANGQNPISQRVQCMLNNSILLRNVSPED 139

Human   484 GTWYRC----MSSTPAGSIEAQARVQVL-EKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIK 543
            ...|.|    .......::...||:.:| :....|...|..:..:..|   :.|.....:..|||
  Fly   140 SDDYYCEILPQRVRQHTALRVGARLSILCDDRDITDRSQTFRQGDHHK---LECRTYLPDNATIK 201

Human   544 WERADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNG----PQGQIRAHVQLTVAVFITFKV 604
            |...|.:..|..|.:..|.:....|...:||:|.|:|.:|    |.|.:...||.:..|    ..
  Fly   202 WSFNDLNGQPSSVDNQNGVIILDNVDEKNAGDYQCLADDGSRHPPHGTVHIDVQYSPIV----ST 262

Human   605 EPERTTVYQGHTALLQCEAQGDP--KPLIQWKGKD-RILDPTKLGPRMHIFQN-GSLVIHDVAPE 665
            ........:|.||.|.|..:..|  :......||. ::.|...|...:|...| .:|::.:|...
  Fly   263 HRHNVNTEKGATAELYCNYRAKPIGRSYFIKDGKTLQLSDKYSLKDSVHNDHNRTTLIVREVTDS 327

Human   666 DSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESE 699
            |.|.|.|...|:  |...|..::|...|...:.|
  Fly   328 DLGEYLCQVENA--IGSNEVKVHVSYNPETPQFE 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTK7	NP_001257327.1	Ig_3	41..112	CDD:464046
		Ig2_PTK7	136..230	CDD:409417
		Ig strand B	154..158	CDD:409417
		Ig strand C	167..171	CDD:409417
		Ig strand E	191..195	CDD:409417
		Ig strand F	205..210	CDD:409417
		Ig strand G	217..220	CDD:409417
		Ig_3	234..310	CDD:464046
		Ig	337..409	CDD:472250
		Ig strand C	361..365	CDD:409389
		Ig strand E	382..386	CDD:409389
		Ig strand F	396..401	CDD:409389
		Ig	420..506	CDD:472250	22/90 (24%)
		Ig strand B	437..441	CDD:409353	2/6 (33%)
		Ig strand C	450..454	CDD:409353	2/3 (67%)
		Ig strand E	472..476	CDD:409353	0/3 (0%)
		Ig strand F	486..491	CDD:409353	2/8 (25%)
		Ig strand G	499..502	CDD:409353	0/2 (0%)
		Ig	528..592	CDD:409353	18/67 (27%)
		Ig strand B	528..532	CDD:409353	0/3 (0%)
		Ig strand C	541..545	CDD:409353	3/3 (100%)
		Ig strand E	561..565	CDD:409353	1/3 (33%)
		Ig strand F	575..580	CDD:409353	2/4 (50%)
		Ig strand G	589..592	CDD:409353	0/2 (0%)
		Ig_3	601..676	CDD:464046	18/78 (23%)
		PTK_CCK4	798..1071	CDD:133178
CG13506	NP_611666.2	Ig_3	69..146	CDD:464046	19/70 (27%)
		Ig_3	173..238	CDD:464046	17/67 (25%)
		Ig	258..349	CDD:472250	22/96 (23%)
		Ig strand B	275..279	CDD:409353	2/3 (67%)
		Ig strand C	288..292	CDD:409353	0/3 (0%)
		Ig strand E	317..321	CDD:409353	1/3 (33%)
		Ig strand F	331..336	CDD:409353	2/4 (50%)