Protein Alignment JYalpha and atp1a1b

DIOPT Version :10

• Sequence 1: NP_001104092.2
• Gene: JYalpha / 5740846
• FlyBaseID: FBgn0267363
• Length: 1009
• Species: Drosophila melanogaster
• Sequence 2: NP_571765.1
• Gene: atp1a1b / 64616
• ZFINID: ZDB-GENE-001212-5
• Length: 1025
• Species: Danio rerio
• Alignment Length: 1011
• Identity: 636/1011 - (62%)
• Similarity: 785/1011 - (77%)
• Gaps: 11/1011 - (1%)

  Fly     4 KKKNKEHKINGKEKKKDIQSFKKDVETDNHKIPVDELLERLKTDPNMGLSFVEAKLRLEINGPNI 68
            |||||     .|:|:||:...||:|:.|:||:.::||..:..||.|.||:...|...|..:|||.
Zfish    21 KKKNK-----NKKKEKDMDELKKEVDLDDHKLTLEELNRKYGTDLNRGLTTARAAEILARDGPNA 80

  Fly    69 LTPQPPTPKWIVFLKTMFGGFAILLWAGSFLCFVGYLIQLQTQHEPPDDNLYLGIALTVLVIVTG 133
            |||.|.||:|:.|.|.|||||::|||.|:.|||:.|.||...:.||.:||||||:.|:.:||:||
Zfish    81 LTPPPTTPEWVKFCKQMFGGFSMLLWTGALLCFLAYGIQAAMEDEPANDNLYLGVVLSAVVIITG 145

  Fly   134 LFTYFQVHKSSSIMDSFKNLVPQYATVIREGEINTVTSDEIVKGDIVEVKFGDRVPADIRILEAH 198
            .|:|:|..|||.|||||||||||.|.|:|:||.|.|.::|:|.||:||||.|||:|||:||:.:|
Zfish   146 CFSYYQEAKSSKIMDSFKNLVPQQALVVRDGEKNHVNAEEVVVGDLVEVKGGDRIPADLRIIASH 210

  Fly   199 GLKVDNSSLTGESEPQVRSTEFTHENPLETKNLAFFSTNVLEGTCRGVVIATGDSTVMGRIANLA 263
            |.||||||||||||||.||.:::::|||||:|:||||||.:|||.||:||:|||.|||||||.||
Zfish   211 GCKVDNSSLTGESEPQTRSPDYSNDNPLETRNIAFFSTNCVEGTARGIVISTGDRTVMGRIATLA 275

  Fly   264 AGLDDVQSPISREIQLFIRFITIFAIILGLSFFAISLTLGYEFIDAVVFLIGIIVANVPEGLLVT 328
            :||:..::|||.||:.||..||..|:.||:|||.:||.|||.:::||:|||||||||||||||.|
Zfish   276 SGLEVGRTPISIEIEHFIHIITGVAVFLGVSFFVLSLALGYSWLEAVIFLIGIIVANVPEGLLAT 340

  Fly   329 VTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLWYDQIIVESDTTE 393
            |||||||||||||.|||||||||||||||||||||||||||||||||||||:|:|..|.|:||||
Zfish   341 VTVCLTLTAKRMAKKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTE 405

  Fly   394 SFRGSHFKIEDKSFNALFMCAALCNSAEFKGGQDDIPVFKKDVNGNASEAALLKFTETIFAGIGA 458
            :..|:.|.....::.:|...|.|||.|.|...|.|:|:.|:||.|:|||:||||..|.....:..
Zfish   406 NQSGTSFDRSSATWASLARVAGLCNRAVFLAEQTDVPILKRDVAGDASESALLKCIELCCGSVKD 470

  Fly   459 FRQKHIKLTEIPFNSTEKYQVSVHEFNSSDG---YFIVEMKGAPERILDRCSTIIIQGLSVELTP 520
            .|:|:.|:.|||||||.|||:|||: |.:.|   ..::.|||||||||||||||:|||....|..
Zfish   471 MREKYTKVAEIPFNSTNKYQLSVHK-NPNGGTESKHLLVMKGAPERILDRCSTILIQGKVQALDD 534

  Fly   521 TLKLEFEEAYLEMGGMGERVLGFADLLLPMSKYPISYEFSADPPNFPLENLRFLGLISLIDPPRA 585
            .:|..|:.||||:||:|||||||....||..::|..:.|..:..|||.|||.|:||:|:||||||
Zfish   535 EMKEAFQNAYLELGGLGERVLGFCHFCLPDEEFPEGFPFDTEDVNFPTENLCFVGLMSMIDPPRA 599

  Fly   586 AVPDAVAKCRSAGVRVIMVTGDHPITAKAIARSVGIIT--TPTAEDIAKQRGVTVLDIDSRQATA 648
            ||||||.||||||::||||||||||||||||:.||||:  ..|.||||.:..:.|.:::.|.|.|
Zfish   600 AVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVNEVNPRDAKA 664

  Fly   649 IVVHGGELREMKAEELDAVIYYHNEIVFARTSPQQKLIIVEACQRRGEIVAVTGDGVNDSPALKR 713
            .|||||:|:::..|:||.::.:|.|||||||||||||||||.|||:|.||||||||||||||||:
Zfish   665 CVVHGGDLKDLSCEQLDDILKHHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKK 729

  Fly   714 ADIGVAMGISGSDVSKQAADMILLDDNFASIVVGIEEGRIIFDNLKKSIAYTLTSNLPEIVPFLF 778
            |||||||||:||||||||||||||||||||||.|:||||:||||||||||||||||:|||.|||.
Zfish   730 ADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLL 794

  Fly   779 FVIFDIPLALGTIAILCIDIGTDMLPAISLAYEKAESDIMARMPRDPFEDRLVNKKLILMAYLQI 843
            |:|.:|||.|||:.|||||:|||||||||||||.||||||.|.||:|..|:|||::||.:||.||
Zfish   795 FIIANIPLPLGTVTILCIDLGTDMLPAISLAYEAAESDIMKRQPRNPKTDKLVNERLISIAYGQI 859

  Fly   844 GVIQTVACFFTFFAIMAEHGFPPSRLKGIREDWDSKNVEDLEDGYGQEWTYRERKVLEYTAGTGF 908
            |:||.:|.|||:|.|::|:||.||||.|||..||.|::.||||.|||:|||.:||::|:|..|.|
Zfish   860 GMIQALAGFFTYFVILSENGFLPSRLLGIRVYWDDKHINDLEDSYGQQWTYEQRKIVEFTCHTAF 924

  Fly   909 FVSIVVTQVFDLLICKTRRNSILQQGMGNHVLNFALVLEFIIACLLCYVPVFEKTLRMYSIKFIW 973
            |.||||.|..||:||||||||:.||||.|.:|.|.|..|..:|..|.|.|..:..||||.:|..|
Zfish   925 FASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPNW 989

  Fly   974 WIYAFPFGLLIFFFDESRRFLIRRNPGGWVEQETYY 1009
            |..|||:.||||.:||.|:.::|||||||||:||||
Zfish   990 WFCAFPYSLLIFIYDEMRKLILRRNPGGWVERETYY 1025

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JYalpha	NP_001104092.2	P-type_ATPase_Na-K_like	51..1006	CDD:319794	612/959 (64%)
atp1a1b	NP_571765.1	ATPase-IIC_X-K	32..1025	CDD:273445	626/993 (63%)