Protein Alignment JYalpha and Atp12a

DIOPT Version :10

• Sequence 1: NP_001104092.2
• Gene: JYalpha / 5740846
• FlyBaseID: FBgn0267363
• Length: 1009
• Species: Drosophila melanogaster
• Sequence 2: NP_619593.2
• Gene: Atp12a / 192113
• MGIID: 1926943
• Length: 1035
• Species: Mus musculus
• Alignment Length: 1015
• Identity: 549/1015 - (54%)
• Similarity: 732/1015 - (72%)
• Gaps: 11/1015 - (1%)

  Fly     4 KKKNKEHKINGKEK-----KKDIQSFKKDVETDNHKIPVDELLERLKTDPNMGLSFVEAKLRLEI 63
            :|.:|:.| .||.|     |...:..||:::.|:|::...:|.::..|:...|||.:.|...|..
Mouse    23 QKDDKKFK-GGKNKDSEPNKSQEEELKKELDLDDHRLSNTDLEQKYGTNIIQGLSSIRAAELLAR 86

  Fly    64 NGPNILTPQPPTPKWIVFLKTMFGGFAILLWAGSFLCFVGYLIQLQTQHEPPDDNLYLGIALTVL 128
            :|||.|||...||:.|.|||.|.|||:||||.|:.||::.|:|| ........||:|||..|.::
Mouse    87 DGPNALTPPKQTPEIIKFLKQMVGGFSILLWIGAALCWIAYVIQ-YVSSTASLDNVYLGAILVLV 150

  Fly   129 VIVTGLFTYFQVHKSSSIMDSFKNLVPQYATVIREGEINTVTSDEIVKGDIVEVKFGDRVPADIR 193
            ||:||:|.|:|..||::||.||..::||.|.|||:.|...:.::::|.||:||:|.||::|||||
Mouse   151 VILTGIFAYYQEAKSTNIMASFSKMIPQQALVIRDAEKKIIPAEQLVVGDVVEIKGGDQIPADIR 215

  Fly   194 ILEAHGLKVDNSSLTGESEPQVRSTEFTHENPLETKNLAFFSTNVLEGTCRGVVIATGDSTVMGR 258
            ::.:.|.||||||||||||||.|||||||||||||||:.|:||..||||..|:||.|||.|::||
Mouse   216 LVFSQGCKVDNSSLTGESEPQARSTEFTHENPLETKNIGFYSTTCLEGTATGIVINTGDRTIIGR 280

  Fly   259 IANLAAGLDDVQSPISREIQLFIRFITIFAIILGLSFFAISLTLGYEFIDAVVFLIGIIVANVPE 323
            ||:||:|:...::||:.||:.|:..:...|:.:|:.||..::.:.|..:||::|||.||||||||
Mouse   281 IASLASGVGSEKTPIAIEIEHFVHIVAAVAVSVGVIFFITAVCMKYYVLDAIIFLISIIVANVPE 345

  Fly   324 GLLVTVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLWYDQIIVE 388
            |||.||||.|:|||||||.||||||||||||||||||.||||||||||||||||||||:|..|..
Mouse   346 GLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFV 410

  Fly   389 SDTTESFRGSHFKIEDKSFNALFMCAALCNSAEFKGGQDDIPVFKKDVNGNASEAALLKFTETIF 453
            :||:|:.....|.....::.:|.....|||.|||:.||:.:|:.|:.|.|:|||.|||||:|.|.
Mouse   411 ADTSENQTKQAFDQSSGTWASLSKIITLCNRAEFRPGQESVPIMKRVVVGDASETALLKFSEVIL 475

  Fly   454 AGIGAFRQKHIKLTEIPFNSTEKYQVSVHEF-NSSDGYFIVEMKGAPERILDRCSTIIIQGLSVE 517
            ..:...|:::.|:.|||||||.|:|:|:||. :.:|..|::.|||||||||::||||:|.|....
Mouse   476 GDVMDIRKRNHKVAEIPFNSTNKFQLSIHETEDPNDKRFLMVMKGAPERILEKCSTIMINGQEQP 540

  Fly   518 LTPTLKLEFEEAYLEMGGMGERVLGFADLLLPMSKYPISYEFSADPPNFPLENLRFLGLISLIDP 582
            |..:....|..||:|:||:|||||||..|.||..|:|.||.|..|..|||..||.|:||:|:|||
Mouse   541 LDKSSADAFHTAYMELGGLGERVLGFCHLYLPADKFPQSYTFDVDSINFPTSNLCFVGLLSMIDP 605

  Fly   583 PRAAVPDAVAKCRSAGVRVIMVTGDHPITAKAIARSVGIIT--TPTAEDIAKQRGVTVLDIDSRQ 645
            ||:.|||||:||||||::||||||||||||||||:|||||:  ..|.|||||:|.:.|..::.|:
Mouse   606 PRSTVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANNETVEDIAKRRNIAVEQVNKRE 670

  Fly   646 ATAIVVHGGELREMKAEELDAVIYYHNEIVFARTSPQQKLIIVEACQRRGEIVAVTGDGVNDSPA 710
            |.|.||.|.||::|..|:||.::..:.|||||||||||||||||.|||:..:|||||||||||||
Mouse   671 AKAAVVTGMELKDMTPEQLDELLINYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPA 735

  Fly   711 LKRADIGVAMGISGSDVSKQAADMILLDDNFASIVVGIEEGRIIFDNLKKSIAYTLTSNLPEIVP 775
            ||:||||:||||:|||.:|.||||:||||||||||.|:||||:|||||||:||||||.|:.|:.|
Mouse   736 LKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYTLTKNIAELCP 800

  Fly   776 FLFFVIFDIPLALGTIAILCIDIGTDMLPAISLAYEKAESDIMARMPRDPFEDRLVNKKLILMAY 840
            ||.:::..:||.:|||.||.||:|||::|:|:|||||||||||.|.||...:||||||:|.:.:|
Mouse   801 FLIYIVAGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKKKDRLVNKQLAIYSY 865

  Fly   841 LQIGVIQTVACFFTFFAIMAEHGFPPSRLKGIREDWDSKNVEDLEDGYGQEWTYRERKVLEYTAG 905
            |.||::|.:..|..:|.:.|:.||.|:.|..:|..|::.::.||||.||||||..:||.||:|..
Mouse   866 LHIGLMQALGGFLVYFTVYAQQGFWPTSLINLRVSWETDDINDLEDSYGQEWTRYQRKYLEWTGS 930

  Fly   906 TGFFVSIVVTQVFDLLICKTRRNSILQQGM-GNHVLNFALVLEFIIACLLCYVPVFEKTLRMYSI 969
            |.|||:|:|.|:.||:|.|||||||.|||: .|.|:...::.:.|:|.:|.|.......|....:
Mouse   931 TAFFVAIMVQQIADLIIRKTRRNSIFQQGLFRNKVIWVGIISQIIVALVLSYGLGSVTALSFTML 995

  Fly   970 KFIWWIYAFPFGLLIFFFDESRRFLIRRNPGGWVEQETYY 1009
            :..:|..|.|..:||:.:||.|:..||..||.|.::..||
Mouse   996 RAQYWFVAVPHAILIWVYDEMRKLFIRLYPGSWWDKNMYY 1035

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JYalpha	NP_001104092.2	P-type_ATPase_Na-K_like	51..1006	CDD:319794	534/958 (56%)
Atp12a	NP_619593.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	22..49		7/26 (27%)
		ATPase-IIC_X-K	40..1035	CDD:273445	541/995 (54%)