DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34425 and cfap53

DIOPT Version :9

Sequence 1:	NP_001097683.1	Gene:	CG34425 / 5740837	FlyBaseID:	FBgn0085454	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	NP_001038595.2	Gene:	cfap53 / 567344	ZFINID:	ZDB-GENE-060503-508	Length:	519	Species:	Danio rerio

Alignment Length:	436	Identity:	107/436 - (24%)
Similarity:	185/436 - (42%)	Gaps:	124/436 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 KAKEVTA----AELHERSKRLKNMLDEEDKRYEEEFSNTVKNRIDQDIKERKEHLHAIKEQVAKQ 92
            :||:.|.    |::||.:|.|:       :|.|.|....|.:::||..:|:.|.|.|:  |:.::
Zfish   117 EAKKETVLERQAKMHEGAKTLR-------ERRESERQRVVADKLDQLFREQSEELRAV--QIKRR 172

  Fly    93 QKKFLEEKHIQQVMLDCYEIREALRHQDLVETKIVQEEQILENQRKKRRECQQDNYWLELNRRRW 157
            |         .||   |.|....:|.::.|.....:||::.....:..|..:::.:.|||.|
Zfish   173 Q---------DQV---CTERESQIRTKEEVRRVQEEEEKLFAQMWESDRLAKEERHNLELQR--- 222

  Fly   158 AQFDCNQAEENQRRHQMQQQVNHVLAVQVAEHEEKRKAALAERMEDERLINSLLEEIRLEEFEKE 222
                       ||.:.:||:.  ||..|:...|::|..|...:.|:.:|:....|.:|||. |:|
Zfish   223 -----------QRENNLQQKA--VLQTQMDMAEQQRIQAKELKQEEAQLLKDQREMLRLEA-ERE 273

  Fly   223 HQAAPVDQ------------------------------------LAY-----QDELLKEIER-KR 245
            |:....||                                    ||.     |||:||::|| :.
Zfish   274 HRQKLQDQEKRRKQLDLSLRLKMKRLTRDRQEELALDMSILEQLLAQEKDEKQDEVLKKLERQEE 338

  Fly   246 CARLAEWEAEKANHVAFCRETQRLEAEALANIAQSKKDLNRATLEYLAYLRRMQSLELGIEKMMD 310
            ..|..|:..::      ..|.:|||||.        :.|..:.|:. |:.||  ..:..:||...
Zfish   339 QRRYREYLTQQ------LEEQKRLEAET--------EQLFESELQQ-AWARR--EAQWRLEKTAR 386

  Fly   311 ERIADLYQLDMCTKVNITERVRVKREAAEKCHEILRKQICEDYERKIRSDAELRENKMMENRFVH 375
            :|:..          ::.:.:|:  :..||.:|.::|| .|.::.|...|..::.||:::..
Zfish   387 DRLMK----------DVMDTLRL--QIQEKLNENMQKQ-AEAFKEKEELDRIIQANKLLDEE--- 435

  Fly   376 PEVTHEMIACRQIQHKADLDAQIKEMKRIQE----EEEKRFDSRLM 417
             |..|...|.::.|  |||.||:...:||:|    |:|..|...||
Zfish   436 -EKAHFREATKEYQ--ADLLAQMMYRQRIREAEEAEKEYEFQKGLM 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34425	NP_001097683.1	PTZ00121	<29..402	CDD:173412	99/415 (24%)
cfap53	NP_001038595.2	TPH	160..493	CDD:290579	92/386 (24%)
cfap53	NP_001038595.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	498..519
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52256
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR31183
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.110