DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG34425 and cfap53

DIOPT Version :10

Sequence 1:NP_001097683.1 Gene:CG34425 / 5740837 FlyBaseID:FBgn0085454 Length:532 Species:Drosophila melanogaster
Sequence 2:NP_001120281.1 Gene:cfap53 / 100145337 XenbaseID:XB-GENE-988466 Length:516 Species:Xenopus tropicalis


Alignment Length:474 Identity:113/474 - (23%)
Similarity:214/474 - (45%) Gaps:58/474 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 TDRKSLHTQIGLLVNKAKEVTAAELHERSKRLKNMLDEEDKRYEEEFSNTVKNRIDQDIKERKEH 81
            |::|.||..:...|.:..:.....|.||.:||..:|:.|:..:.:|.....:..:::..|.| |.
 Frog    71 TEKKLLHNTVQRAVYRTMQEYKMHLEERRERLSTLLEREEMEHIKEMEAMEETTLERQAKMR-ER 134

  Fly    82 LHAIKEQVAKQQKKFLEEKHIQQVMLDCYEIREALR---HQDLVETKIVQEEQILENQRKKRREC 143
            :.:::|:..|::..|:.||..||....|.|:| :||   |.:.|.|:.:.:..:.|...::|:| 
 Frog   135 VKSLREKREKERMDFVAEKREQQFRDQCEELR-SLRSQIHLNEVCTERMAQIALKEEINRQRKE- 197

  Fly   144 QQDNYWLELNRRRWAQFDCNQAEENQRRHQMQQQVNHVLA-VQVAEHEEKRKAALAERMEDERLI 207
             :|..:.:|    |......:.|:.:::.|.:.::|..:| :|.|..|.::......:.|:.:|:
 Frog   198 -EDTIFDQL----WEHDRLAKEEQEEKKRQKRMELNQEIASLQKAASEAQKMQEKWLKDEESKLV 257

  Fly   208 NSLLEEIRLEEFEKEHQAAPVDQLAYQ-DELLKEIERKRCARLAEWEAEKANHVAFCRETQRLEA 271
               .||.||.:.|:|.......|...| ..:|::..|.:..|||..:.|:.          .|:.
 Frog   258 ---AEERRLIKLEEERSLKEKQQNRLQVKSMLEDSIRLKMKRLAREQQEEL----------ALDM 309

  Fly   272 EALANIAQS-----------KKDLNRATLEYLAYLRRMQSLELGIEKMMDERIADLYQLDMCTKV 325
            :.|.::.|.           |.:|.:....|..||.:....|...|:.||:.|....:.....| 
 Frog   310 KILEHVMQGYQDDTEEKRQRKMELKKEQQIYREYLAQQLEEEKRQEREMDKMIEAELEKSWAKK- 373

  Fly   326 NITERVRVKREAAEK----CHEILRKQICEDYERKIRSDAELRENKMMENRFV--HPEVTHEMIA 384
              ||::|.::||..:    ..::.|.||.|..|:..:...||.::|.:..|..  |.::..|..|
 Frog   374 --TEQMRKEKEARNRLMKDVMDMRRVQIQEKLEKNAKLQEELAQDKELLQRATEEHKQLETERNA 436

  Fly   385 CRQI----QHKADLDAQI---KEMKRIQEEEEKRFDSRLMAAVDDPVLCKRLAKEILDNG-VDYL 441
             ||:    |::.||.:|:   :..::.:.|||:|.....|||   ....:...:|||... |.:.
 Frog   437 -RQMNLAQQYQQDLLSQVAYQQWQRQAEREEEQREYEAGMAA---EKAYQNTLREILSRPYVGHE 497

  Fly   442 APHPNWRVMACNPNKYIPR 460
            ..||..|....:|..::|:
 Frog   498 NIHPLRRGRISSPKDWLPQ 516

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG34425NP_001097683.1 Smc 69..>316 CDD:440809 60/262 (23%)
cfap53NP_001120281.1 DUF5401 <52..>253 CDD:375164 44/189 (23%)
TPH 159..491 CDD:464007 84/358 (23%)

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