DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34297 and si:dkey-33c12.4

DIOPT Version :9

Sequence 1:	NP_001097696.1	Gene:	CG34297 / 5740802	FlyBaseID:	FBgn0085326	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	XP_021336269.1	Gene:	si:dkey-33c12.4 / 560112	ZFINID:	ZDB-GENE-030131-2527	Length:	648	Species:	Danio rerio

Alignment Length:	219	Identity:	42/219 - (19%)
Similarity:	87/219 - (39%)	Gaps:	61/219 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IDECFLDSESTVEEVVRLLENLQVPNEEEAEGQEKPKRSLKSSTITEESFIITERKTPIP---VI 70
            ::.||:.:.:.:.:  |.||  |.|..::...|..||:..:|.          ::.|.:|   |.
Zfish   246 MNSCFVSNAAAIAK--RKLE--QKPKPDKKPAQANPKKQHESQ----------QKATVMPQKQVA 296

  Fly    71 SAPTSSKEKSKPRTFNRIDRSKDRFPFMRQVEMDLDQRSKARLERERVAQNFRKLGNAEYRKGNY 135
            ....:.:|......|           ..|.||:.:                   :||.....||.
Zfish   297 KEEVNGEESVNANDF-----------ITRSVELAV-------------------IGNEYAGSGNM 331

  Fly   136 EAAMKVYTEAIENIRDSHILYINRALCFIKSGKFKRGIVDCDFVLNKLDEKNLRAWMYRAMAYKG 200
            |.|:|.:|:||::....:.|:.||:.|:.|..::::.:.|.:..|: ::.|.::....:..|..|
Zfish   332 EMAVKYFTDAIKHNPKEYKLFGNRSYCYEKMLQYEKSLTDAEIALS-MNPKWIKGLYRKGRALVG 395

  Fly   201 LNDESNFENCVKYARKFNSKQMDF 224
            |             :::|..::.|
Zfish   396 L-------------KRYNEARLTF 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34297	NP_001097696.1	TPR_11	119..185	CDD:290150	17/65 (26%)
		TPR repeat	119..147	CDD:276809	9/27 (33%)
		TPR repeat	152..183	CDD:276809	7/30 (23%)
		TPR repeat	188..216	CDD:276809	3/27 (11%)
si:dkey-33c12.4	XP_021336269.1	PLN03088	258..>439	CDD:330826	40/207 (19%)
		TPR repeat	348..378	CDD:276809	7/30 (23%)
		TPR repeat	383..411	CDD:276809	5/37 (14%)
		UBA	430..456	CDD:270456
		RRM	<471..>614	CDD:223796
		RRM	519..584	CDD:214636
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0548
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900