DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34451 and B3GLCT

DIOPT Version :9

Sequence 1:	NP_001369052.1	Gene:	CG34451 / 5740612	FlyBaseID:	FBgn0085480	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_919299.3	Gene:	B3GLCT / 145173	HGNCID:	20207	Length:	498	Species:	Homo sapiens

Alignment Length:	254	Identity:	52/254 - (20%)
Similarity:	109/254 - (42%)	Gaps:	48/254 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FLILTLYINVSEVDRKPAKRSNQHTLDPLYEEIRILCMIPYNYNSPDTAKYVKRTWGKHCNVLLF 82
            |...|.:.:...:.|||.|:          ::|.:.......::. |....||:||....:::.:
Human   247 FYCATTFHSFLPLCRKPVKK----------KDIFVAVKTCKKFHG-DRIPIVKQTWESQASLIEY 300

  Fly    83 VSGDIDGELEPYVPV-INSTD------TWTLVQQGLMQAYLFYADQIDWFLRVEPSSFVVLENLR 140
            .|...:..: |.|.: |.:||      |:.::::.|.::    .|:..|.:.|:..:.:.:..|:
Human   301 YSDYTENSI-PTVDLGIPNTDRGHCGKTFAILERFLNRS----QDKTAWLVIVDDDTLISISRLQ 360

  Fly   141 YMIHKRKYQPSQPIY----FGYELENIVTHESFVHHHSGYVISREALRRYTMASKDPENKECTHW 201
            :::  ..|...:|::    :||.|.  ....|::....|.|.||||:|| .:|||      |..:
Human   361 HLL--SCYDSGEPVFLGERYGYGLG--TGGYSYITGGGGMVFSREAVRR-LLASK------CRCY 414

  Fly   202 EGYV-EGLDIHRCLRFANVTVAESRDEFEHETFLPVTMDYQFLNGYDTIPWLRKLSYHK 259
            .... :.:.:..|  |:.:.:..:.....|:. .||.....:|:  ..:|    :|:||
Human   415 SNDAPDDMVLGMC--FSGLGIPVTHSPLFHQA-RPVDYPKDYLS--HQVP----ISFHK 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34451	NP_001369052.1	None
B3GLCT	NP_919299.3	Galactosyl_T	264..467	CDD:304462	47/237 (20%)
B3GLCT	NP_919299.3	Prevents secretion from ER	495..498
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2246
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810