Protein Alignment CG34451 and B3GLCT

DIOPT Version :10

• Sequence 1: NP_001369052.1
• Gene: CG34451 / 5740612
• FlyBaseID: FBgn0085480
• Length: 307
• Species: Drosophila melanogaster
• Sequence 2: NP_919299.3
• Gene: B3GLCT / 145173
• HGNCID: 20207
• Length: 498
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 52/254 - (20%)
• Similarity: 109/254 - (42%)
• Gaps: 48/254 - (18%)

  Fly    18 FLILTLYINVSEVDRKPAKRSNQHTLDPLYEEIRILCMIPYNYNSPDTAKYVKRTWGKHCNVLLF 82
            |...|.:.:...:.|||.|:          ::|.:.......::. |....||:||....:::.:
Human   247 FYCATTFHSFLPLCRKPVKK----------KDIFVAVKTCKKFHG-DRIPIVKQTWESQASLIEY 300

  Fly    83 VSGDIDGELEPYVPV-INSTD------TWTLVQQGLMQAYLFYADQIDWFLRVEPSSFVVLENLR 140
            .|...:..: |.|.: |.:||      |:.::::.|.::    .|:..|.:.|:..:.:.:..|:
Human   301 YSDYTENSI-PTVDLGIPNTDRGHCGKTFAILERFLNRS----QDKTAWLVIVDDDTLISISRLQ 360

  Fly   141 YMIHKRKYQPSQPIY----FGYELENIVTHESFVHHHSGYVISREALRRYTMASKDPENKECTHW 201
            :::  ..|...:|::    :||.|.  ....|::....|.|.||||:|| .:|||      |..:
Human   361 HLL--SCYDSGEPVFLGERYGYGLG--TGGYSYITGGGGMVFSREAVRR-LLASK------CRCY 414

  Fly   202 EGYV-EGLDIHRCLRFANVTVAESRDEFEHETFLPVTMDYQFLNGYDTIPWLRKLSYHK 259
            .... :.:.:..|  |:.:.:..:.....|:. .||.....:|:  ..:|    :|:||
Human   415 SNDAPDDMVLGMC--FSGLGIPVTHSPLFHQA-RPVDYPKDYLS--HQVP----ISFHK 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34451	NP_001369052.1	None
B3GLCT	NP_919299.3	Fringe	264..467	CDD:367085	47/237 (20%)
		Prevents secretion from ER	495..498