DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fili and Lingo1

DIOPT Version :8

Sequence 1:NP_001097402.1 Gene:Fili / 5740472 FlyBaseID:FBgn0085397 Length:738 Species:Drosophila melanogaster
Sequence 2:NP_001094192.1 Gene:Lingo1 / 315691 RGDID:1308668 Length:620 Species:Rattus norvegicus

Alignment Length:409 Identity:125/410 (30%)
Similarity:184/410 (45%) Gaps:50/410 (12%)


  Fly    22 PVLLLLLLTLVILPPETTAFCPSKCQCLGGEANSRA-LCVDAALEDVPIQLNPETKYINLTVNRI 85
            |:|||:|.:  :|....|. ||.:|:|   .|..|| ||.......||..:..||:.::|..|||
  Rat    25 PILLLVLGS--VLSGSATG-CPPRCEC---SAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRI 83

  Fly    86 RTL---EF-SLPFYMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLTNL 146
            :||   || |.|   .||.|:|::||:..:....|.....||||.|..|.:..:....|.||:||
  Rat    84 KTLNQDEFASFP---HLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNL 145

  Fly   147 LLLDLSFNRIETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPASN 211
            ..||:|.|:|..:......||.:|..|::.:|::|.:....|.|:|:||.|......|..:|...
  Rat   146 TKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEA 210

  Fly   212 LWHLHALKSLDMSLNLVEFVRNDSFEGLKELLALSV-QGNVMSELDLSAFEGLISLKHLDLSDNN 275
            |.|||.|..|.:....:..:|:.||:.|..|..|.: ....:..:..:...|| :|..|.::..|
  Rat   211 LSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGL-NLTSLSITHCN 274

  Fly   276 LTMVPTQQLSKLSNLTYLNLGGNRFSQLPAVAFLNLFHLRELHLSRLDFLQRIDSRAFVDNTHLQ 340
            ||.||...:..|..|.:|||..|....:.......|..|:|:.|.                    
  Rat   275 LTAVPYLAVRHLVYLRFLNLSYNPIGTIEGSMLHELLRLQEIQLV-------------------- 319

  Fly   341 TLHLNNNPQLSDIPMRLFQGNPNILEVYMQSNSLQTLYSAQF-PVDQLQKLYLGDNPLQCNCSLL 404
                  ..||:.:....|:|...:..:.:..|.|.||..:.| .|..|:.|.|..|||.|:|.||
  Rat   320 ------GGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESAFHSVGNLETLILDSNPLACDCRLL 378

  Fly   405 WL----WRLVTGNFEGVDP 419
            |:    |||   ||....|
  Rat   379 WVFRRRWRL---NFNRQQP 394

Known Domains:


GeneSequenceDomainRegion External IDIdentity
FiliNP_001097402.1 leucine-rich repeat 75..97 CDD:275378 11/26 (42%)
LRR_RI 79..327 CDD:238064 78/253 (31%)
leucine-rich repeat 98..121 CDD:275380 7/23 (30%)
LRR_8 120..180 CDD:290566 21/60 (35%)
leucine-rich repeat 122..145 CDD:275380 9/23 (39%)
leucine-rich repeat 146..169 CDD:275380 8/23 (35%)
LRR_8 169..228 CDD:290566 18/59 (31%)
leucine-rich repeat 170..193 CDD:275380 7/23 (30%)
leucine-rich repeat 194..217 CDD:275380 9/23 (39%)
LRR_8 218..276 CDD:290566 13/59 (22%)
leucine-rich repeat 218..265 CDD:275380 10/48 (21%)
LRR_RI <265..406 CDD:238064 38/142 (27%)
LRR_8 265..321 CDD:290566 17/56 (30%)
leucine-rich repeat 266..289 CDD:275380 8/23 (35%)
leucine-rich repeat 290..313 CDD:275380 6/23 (26%)
leucine-rich repeat 314..338 CDD:275380 3/24 (13%)
LRR_8 337..397 CDD:290566 15/61 (25%)
leucine-rich repeat 339..360 CDD:275380 3/21 (14%)
Lingo1NP_001094192.1 LRR <66..371 CDD:227223 96/335 (29%)
leucine-rich repeat 73..96 CDD:275380 11/26 (42%)
leucine-rich repeat 97..120 CDD:275380 7/23 (30%)
leucine-rich repeat 121..144 CDD:275380 9/23 (39%)
leucine-rich repeat 145..192 CDD:275380 15/47 (32%)
leucine-rich repeat 193..216 CDD:275380 9/23 (39%)
leucine-rich repeat 217..264 CDD:275380 10/48 (21%)
leucine-rich repeat 265..288 CDD:275380 8/23 (35%)
leucine-rich repeat 289..312 CDD:275380 6/23 (26%)
leucine-rich repeat 313..336 CDD:275380 7/49 (14%)
leucine-rich repeat 337..357 CDD:275380 5/20 (25%)
PCC 341..>421 CDD:188093 23/58 (40%)
Ig 439..514 CDD:325142
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E33208_3BH3X
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 T131077
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 O PTHR24373
Phylome 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
33.000

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