DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fili and Lrrc3b

DIOPT Version :9

Sequence 1:	NP_001369108.1	Gene:	Fili / 5740472	FlyBaseID:	FBgn0085397	Length:	789	Species:	Drosophila melanogaster
Sequence 2:	XP_002728222.1	Gene:	Lrrc3b / 305705	RGDID:	1311897	Length:	259	Species:	Rattus norvegicus

Alignment Length:	165	Identity:	51/165 - (30%)
Similarity:	79/165 - (47%)	Gaps:	28/165 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 WLCGAIPVLLLL-LLTLVILPPETTAFCPSKCQCLGGEANSRALCVDAALEDVPIQLNPETKYIN 79
            ||..::.:.||| ...|:||...:.:.||..|.| .........|.:|.|:::|..|.|||
  Rat     7 WLSRSLSMCLLLQSFVLMILCFHSASMCPKGCLC-SSSGGLNVTCSNANLKEIPRDLPPET---- 66

  Fly    80 LTVNRIRTLEFSLPFYMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLT 144
                               .:|.|..|.|.::.::.|:...:||.||||:|.:..:.:|||||:.
  Rat    67 -------------------VLLYLDSNQITSIPNEIFKDLHQLRVLNLSKNGIEFIDEHAFKGVA 112

  Fly   145 NLL-LLDLSFNRIETVHPTALSDLASLVELDLTNN 178
            ..| .||||.|||::||..|.::|.:...  :.||
  Rat   113 ETLQTLDLSDNRIQSVHKNAFNNLKARAR--IANN 145

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fili	NP_001369108.1	leucine-rich repeat	75..97	CDD:275378	1/21 (5%)
		leucine-rich repeat	98..121	CDD:275380	5/22 (23%)
		LRR_8	120..180	CDD:404697	26/60 (43%)
		leucine-rich repeat	122..145	CDD:275380	12/22 (55%)
		leucine-rich repeat	146..169	CDD:275380	12/23 (52%)
		LRR	<161..>354	CDD:227223	4/18 (22%)
		leucine-rich repeat	170..193	CDD:275380	2/9 (22%)
		leucine-rich repeat	194..217	CDD:275380
		leucine-rich repeat	218..265	CDD:275380
		leucine-rich repeat	266..289	CDD:275380
		leucine-rich repeat	290..313	CDD:275380
		leucine-rich repeat	314..338	CDD:275380
		LRR_8	337..397	CDD:404697
		leucine-rich repeat	339..360	CDD:275380
Lrrc3b	XP_002728222.1	LRRNT	33..68	CDD:214470	12/58 (21%)
		leucine-rich repeat	66..89	CDD:275378	6/45 (13%)
		LRR_8	69..125	CDD:404697	23/55 (42%)
		leucine-rich repeat	90..113	CDD:275378	12/22 (55%)
		leucine-rich repeat	115..138	CDD:275378	12/22 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24373
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100