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Protein Alignment Fili and Lrrtm3

DIOPT Version :9

Sequence 1:	NP_001369108.1	Gene:	Fili / 5740472	FlyBaseID:	FBgn0085397	Length:	789	Species:	Drosophila melanogaster
Sequence 2:	NP_848793.1	Gene:	Lrrtm3 / 216028	MGIID:	2389177	Length:	582	Species:	Mus musculus

Alignment Length:	403	Identity:	93/403 - (23%)
Similarity:	162/403 - (40%)	Gaps:	96/403 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 PVLLLLLLTLVILPPETTAFCPSKCQCLGGEANSRALCVDAALEDVPIQLNPETKYINLTVNRIR 86
            |.:||.:|:      .....||..|:|.|    ....|....|:::|..::.....::|..|.::
Mouse    20 PTVLLTMLS------SAERGCPKGCRCEG----KMVYCESQKLQEIPSSISAGCLGLSLRYNSLQ 74

  Fly    87 TLEFSLPFYMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLTNLLLLDL 151
            .|:::                       .|:..::|..|.|..|.:|::.::||.|:..|..|.|
Mouse    75 KLKYN-----------------------QFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELIL 116

  Fly   152 SFNRIETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPASNLWHLH 216
            |.|||..........:.:|..|||:.|.:.||....|:|:..|..|..|:|.|..:|........
Mouse   117 SSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCR 181

  Fly   217 ALKSLDMSLNLVEFVRNDSFEGLKELLALSVQGNVMSELDLSAFEGLISLKHLDLSDNNLTMVPT 281
            .|:.||:..|.:..:..:.|.|:..|..|.::.|..|:|:|:.|..|:||::|.:..|.::::..
Mouse   182 NLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYMQWNKISVIGQ 246

  Fly   282 QQLSKLSNLTYLNLGGNRFSQLPAVAFLNLFHLRELHLSRLDFLQRIDSRAFVDNTHLQTLHLNN 346
            ......|:|..|:|.||                              :..||            :
Mouse   247 TMSWTWSSLQRLDLSGN------------------------------EIEAF------------S 269

  Fly   347 NPQLSDIPMRLFQGNPNILEVYMQSNSLQTLYSAQFPVD---QLQKLYLGDNPLQCN---CSLL- 404
            .|.       :||..||:..:.:.||.|  .:..|..:|   .|..:.|..|..:|:   |||:
Mouse   270 GPS-------VFQCVPNLQRLNLDSNKL--TFIGQEILDSWISLNDISLAGNIWECSRNICSLVN 325

  Fly   405 WLWRLVTGNFEGV 417
            ||     .:|:|:
Mouse   326 WL-----RSFKGL 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fili	NP_001369108.1	LRR	71..>348	CDD:443914	60/276 (22%)
		leucine-rich repeat	75..97	CDD:275378	3/21 (14%)
		leucine-rich repeat	98..121	CDD:275380	1/22 (5%)
		leucine-rich repeat	122..145	CDD:275380	8/22 (36%)
		leucine-rich repeat	146..169	CDD:275380	7/22 (32%)
		leucine-rich repeat	170..193	CDD:275380	9/22 (41%)
		leucine-rich repeat	194..217	CDD:275380	6/22 (27%)
		leucine-rich repeat	218..265	CDD:275380	14/46 (30%)
		leucine-rich repeat	266..289	CDD:275380	3/22 (14%)
		leucine-rich repeat	290..313	CDD:275380	5/22 (23%)
		leucine-rich repeat	314..338	CDD:275380	2/23 (9%)
		LRR_8	337..397	CDD:404697	13/62 (21%)
		leucine-rich repeat	339..360	CDD:275380	2/20 (10%)
Lrrtm3	NP_848793.1	LRRNT	33..61	CDD:214470	8/31 (26%)
		LRR	59..339	CDD:443914	81/354 (23%)
		LRR 1	63..83		4/42 (10%)
		leucine-rich repeat	66..86	CDD:275380	4/42 (10%)
		LRR 2	86..107		7/20 (35%)
		leucine-rich repeat	87..110	CDD:275380	8/22 (36%)
		LRR 3	110..131		7/20 (35%)
		leucine-rich repeat	111..134	CDD:275380	7/22 (32%)
		LRR 4	134..155		8/20 (40%)
		leucine-rich repeat	135..158	CDD:275380	9/22 (41%)
		LRR 5	158..179		6/20 (30%)
		leucine-rich repeat	159..182	CDD:275380	6/22 (27%)
		LRR 6	182..203		5/20 (25%)
		leucine-rich repeat	183..206	CDD:275380	6/22 (27%)
		LRR 7	206..226		6/19 (32%)
		leucine-rich repeat	207..230	CDD:275380	8/22 (36%)
		LRR 8	230..251		4/20 (20%)
		leucine-rich repeat	231..254	CDD:275380	3/22 (14%)
		LRR 9	254..275		8/69 (12%)
		leucine-rich repeat	255..279	CDD:275380	10/72 (14%)
		LRR 10	279..300		5/22 (23%)
		leucine-rich repeat	280..300	CDD:275380	4/21 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	378..410
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Software error:

Can't use an undefined value as an ARRAY reference at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 1034.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.