Protein Alignment Fili and chadlb

DIOPT Version :9

• Sequence 1: NP_001369108.1
• Gene: Fili / 5740472
• FlyBaseID: FBgn0085397
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_001274009.1
• Gene: chadlb / 100330176
• ZFINID: ZDB-GENE-121205-5
• Length: 765
• Species: Danio rerio
• Alignment Length: 748
• Identity: 165/748 - (22%)
• Similarity: 288/748 - (38%)
• Gaps: 209/748 - (27%)

  Fly    19 GAIPVLLLLLLTLVILPPETTAFCPSKCQCLGGEANSRALCVDAALEDVPIQLNPETKYINLTVN 83
            |:||...:::|..:.:....:|.||..|.|  ........||:..|.:||..::      .:||.
Zfish     2 GSIPTWPVIILFALKIHTALSAKCPKVCVC--DSIQLTIACVNKNLTEVPPTID------EITVK 58

  Fly    84 RIRTLEFSLPFYMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLTNLLL 148
                             |||..|.::.|.:..|.:...|..|:|..:.:..:.:.||:.|..|:|
Zfish    59 -----------------LDLRGNDLQELPTGAFAHTPYLTHLSLQNSNIRRVREGAFRKLGRLVL 106

  Fly   149 LDLSFNRIETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPASNLW 213
            |:|:.|:||.::..:...|:||.:|.:..|.:..::...|..:..|.:|...:|:|:.:|
Zfish   107 LNLANNKIEILYQESFDGLSSLKQLIIDRNRVEEIQPGAFSQLGFLNLLSLTHNQLVYIP----- 166

  Fly   214 HLHALKSLDMSLNLVEFVRNDSFEGLKELLALSVQGNVMSELDLSAFEGLISLKHLDLSDNNLTM 278
                               |.:|:||:.:..|.:..|.::.|...||.||.:|..|.|.:|.|..
Zfish   167 -------------------NMAFQGLQNIKWLRLSHNFINYLATEAFAGLFTLTRLSLDNNELQF 212

  Fly   279 VPTQQLSKLSNLTYLNLGGNRFSQL--PAVAFLNLFHLRELHLSRLDFLQRIDSRAFVDNTHLQT 341
            .||:.:::||.:|.|.|..|..:.|  .:|:.|.|.||...|.|..||    .:.|.:.:..|..
Zfish   213 FPTETMTRLSEVTRLELSFNPMTYLGEESVSMLKLTHLLLDHNSLQDF----SNAAILLSPRLTH 273

  Fly   342 LHLNNNPQLSDIPMRLFQ----GNPNILEVYMQSNSLQTLYSAQFPVDQLQKLYLGDNPLQCNCS 402
            |.|::|      .:|:.|    |:|                       :|.:|.|..||:.|:|.
Zfish   274 LDLSHN------QLRILQPMAPGSP-----------------------KLTRLNLAGNPIYCSCY 309

  Fly   403 L--LWLW----RLVTGNFEGVDPGMEHAAGGAVAALAKEADDEELADEATAVASTDDGVAALAAY 461
            |  |..|    |:..|   |...|..|.:|          ::.|:.........:.:  |.|.|.
Zfish   310 LRPLREWATRERVRLG---GTCGGPAHLSG----------ENLEVVQPVNLRCLSQE--AMLKAE 359

  Fly   462 IAEQHIVNALHTTEPSAYE------LATSSSNR-----NSGILRMDR------------------ 497
            :.|| ::.||.|| ||..:      .|..:.||     |.|..::.|
Zfish   360 LEEQ-VLPALPTT-PSPKKGKCPANCACETENRHSSCENKGHTKIPRGFSPDTRLLDLRGNHFHY 422

  Fly   498 ----------QQIGCDIWRDKVRT--------RRKL--LTMSEGEITCPAHIVTVVCAVITCLLV 542
                      :.:...:.|.|:..        .:.|  |.:||.::|             :....
Zfish   423 IPANSFPGTAEVVSLHLQRCKIHDIEDGAFSGMKSLVYLYLSENDLT-------------SLTPE 474

  Fly   543 AMIGISVLYYLRFVKRRRKLLHERGPMRTSKSIINVHDRILQGHNPGGLGLGMSMTLGGGNHVNG 607
            |..|:..|.||. :::.|.....:|..:....::.:|   ::.:....|..|:   |.....:.|
Zfish   475 AFKGLPHLTYLH-LEKNRFTQFPKGAFKLLPGLLALH---MENNAIAKLETGL---LTSAEKLRG 532

  Fly   608 LGMTLNYPHHAQTLQAHHHYHQAMPLQS-HGGNGNHEYQQTTLPQLDKLELERYLAAQTIANEYR 671
            |.:|.|    |.|..|...::.|..|:: |.|:.          :|.::..|.:..|:::|.
Zfish   533 LYLTSN----AITAAAPQAFNPAPDLETLHLGSN----------KLQEVPTEAFSKARSLAE--- 580

  Fly   672 ALKPWELPVK---EADDEP-----EHLYERFDH 696
             ||....|::   ....:|     .|||  .||
Zfish   581 -LKLSHNPIRWIGAGAFQPVGTTLRHLY--LDH 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fili	NP_001369108.1	leucine-rich repeat	75..97	CDD:275378	2/21 (10%)
		leucine-rich repeat	98..121	CDD:275380	6/22 (27%)
		LRR_8	120..180	CDD:404697	18/59 (31%)
		leucine-rich repeat	122..145	CDD:275380	6/22 (27%)
		leucine-rich repeat	146..169	CDD:275380	8/22 (36%)
		LRR	<161..>354	CDD:227223	50/194 (26%)
		leucine-rich repeat	170..193	CDD:275380	4/22 (18%)
		leucine-rich repeat	194..217	CDD:275380	5/22 (23%)
		leucine-rich repeat	218..265	CDD:275380	11/46 (24%)
		leucine-rich repeat	266..289	CDD:275380	8/22 (36%)
		leucine-rich repeat	290..313	CDD:275380	8/24 (33%)
		leucine-rich repeat	314..338	CDD:275380	6/23 (26%)
		LRR_8	337..397	CDD:404697	12/63 (19%)
		leucine-rich repeat	339..360	CDD:275380	6/24 (25%)
chadlb	NP_001274009.1	leucine-rich repeat	58..79	CDD:275380	6/37 (16%)
		LRR_RI	59..307	CDD:238064	78/304 (26%)
		LRR_8	78..138	CDD:290566	18/59 (31%)
		leucine-rich repeat	80..103	CDD:275380	6/22 (27%)
		leucine-rich repeat	104..127	CDD:275380	8/22 (36%)
		LRR_8	126..184	CDD:290566	15/81 (19%)
		leucine-rich repeat	128..151	CDD:275380	4/22 (18%)
		leucine-rich repeat	152..175	CDD:275380	9/46 (20%)
		LRR_8	175..234	CDD:290566	20/58 (34%)
		leucine-rich repeat	176..199	CDD:275380	7/22 (32%)
		leucine-rich repeat	200..223	CDD:275380	8/22 (36%)
		leucine-rich repeat	224..246	CDD:275380	6/21 (29%)
		LRR_8	246..304	CDD:290566	20/90 (22%)
		leucine-rich repeat	247..270	CDD:275380	8/26 (31%)
		TPKR_C2	302..342	CDD:301599	14/52 (27%)
		LRR_RI	408..609	CDD:238064	40/240 (17%)
		leucine-rich repeat	410..433	CDD:275380	0/22 (0%)
		leucine-rich repeat	434..457	CDD:275380	2/22 (9%)
		LRR_8	436..492	CDD:290566	12/69 (17%)
		leucine-rich repeat	458..481	CDD:275380	7/35 (20%)
		LRR_8	480..540	CDD:290566	13/70 (19%)
		leucine-rich repeat	482..505	CDD:275380	5/23 (22%)
		leucine-rich repeat	506..529	CDD:275380	4/28 (14%)
		LRR_8	529..588	CDD:290566	17/76 (22%)
		leucine-rich repeat	530..553	CDD:275380	8/26 (31%)
		leucine-rich repeat	554..577	CDD:275380	6/32 (19%)
		leucine-rich repeat	578..602	CDD:275380	5/27 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24373
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100