Protein Alignment Fili and elfn2

DIOPT Version :8

• Sequence 1: NP_001097402.1
• Gene: Fili / 5740472
• FlyBaseID: FBgn0085397
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: NP_001123827.1
• Gene: elfn2 / 100170580
• XenbaseID: XB-GENE-1001551
• Length: 806
• Species: Xenopus tropicalis
• Alignment Length: 618
• Identity: 133/619 (21%)
• Similarity: 216/619 (35%)
• Gaps: 179/619 (29%)

  Fly    27 LLLTLVILPPETTAFC------PSKCQCLGGEANS--RALCV--DAALEDVPIQLNPETKYINLT 81
            |.||.|..      ||      .|.|..:.||...  .|:|.  ....|.:|..:|.....:.|.
 Frog     6 LWLTTVFF------FCHLPTGARSDCWLIEGEKGYVWLAICSQNQPPYETIPQHINSTVHDLRLN 64

  Fly    82 VNRIRTLEF-SLPFYMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLTN 145
            .|:::.:.: ||..:..|..|:|::|.|..:....|..||.|:.|.|..|.:::|.:...:|:..
 Frog    65 ENKLKIIGYSSLSRFGNLTDLNLTKNEIYYIEDGAFMGQSNLQILYLGYNKLTNLSEGMLRGMPR 129

  Fly   146 LLLLDLSFNRIETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPAS 210
            |..|.:..|.|:.|.|.|.|:..||:.:||::|.|.:|:.:.|.|:.||.|...         |.
 Frog   130 LQFLFVQHNLIDVVTPNAFSECLSLISIDLSSNRIKNLDSSTFAGLQTLMVCEL---------AG 185

  Fly   211 NLWHLHA-----LKSLDMSLNLVEFVRNDSFEGLKELLALSVQGNVMSELDLSAFEGLISLKHLD 270
            |.:|...     |:.|.|..|:   .||  |:.|:          ..:..:.:.|..|....|
 Frog   186 NPFHCGCELYGFLEWLVMFNNV---TRN--FDRLQ----------CETPREFTGFPLLSPRPH-- 233

  Fly   271 LSDNNLTMVPTQQLSKLSNLTYLNLGGNRFSQLPAVAFLNLFHLRELHLSRLDFLQRID-SRAF- 333
            .|.|.:|::.    :...|..:|:|...|.:.|.|                 |.|...| |..|
 Frog   234 HSRNAITVLQ----AHCRNGGHLHLPRERPTSLSA-----------------DSLHETDESSGFN 277

  Fly   334 -VDNTHLQTLHLNNNPQLSDIPMRLFQGNPNILEVYMQSNSLQTLYSAQFPVDQLQKLYLGDNPL 397
             .|....:|......|..|        |.|.|...::..||...:.:..:|   .||||:   .:
 Frog   278 AGDILSPETTTPTPTPDSS--------GGPTIDIHHVTGNSATLIVTIPYP---FQKLYV---LV 328

  Fly   398 QCNCSLLWLWRLVTGNFEGVDPGMEHAAGGAVAALAKEADDEELADEATAVASTDDGVAALAAYI 462
            |.|.|.::                                      :.|.:....:       ||
 Frog   329 QYNNSFVY--------------------------------------DVTTLKHKKE-------YI 348

  Fly   463 AEQHIVNALHTTEPSA-YELATSSSNRNSGILRMDRQQIGCDIWRDKVRTRRKLLTMSEGEITCP 526
                   .|...:|.. |....:|      |....|....|.....::|..:.....:.   |..
 Frog   349 -------TLDKLKPHVNYTFCVTS------IRFSKRYNHTCLFLATRIRDEKDFAPSTS---TTT 397

  Fly   527 AHIVTVVCAVITCLLVAMIGISVLYYLRFVKRRRKLLHERGPMRTSKSIINVHDRILQGHNPGGL 591
            .:|:|    ::.||...:|.:.|:||   ..|::::..|:      |..:||...||:..    .
 Frog   398 HYIMT----ILGCLFGMVIILGVVYY---CLRKKRMQEEK------KKSLNVKKTILEMR----Y 445

  Fly   592 GLGMSMTLGGGNHVNGLGMTLNYPHHAQTLQAH 624
            |..:...||              ||.:|.|..|
 Frog   446 GSDVDPCLG--------------PHSSQKLSEH 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fili	NP_001097402.1	leucine-rich repeat	75..97	CDD:275378	4/23 (17%)
		LRR_RI	79..327	CDD:238064	63/254 (25%)
		leucine-rich repeat	98..121	CDD:275380	8/23 (35%)
		LRR_8	120..180	CDD:290566	20/60 (33%)
		leucine-rich repeat	122..145	CDD:275380	6/23 (26%)
		leucine-rich repeat	146..169	CDD:275380	8/23 (35%)
		LRR_8	169..228	CDD:290566	19/64 (30%)
		leucine-rich repeat	170..193	CDD:275380	8/23 (35%)
		leucine-rich repeat	194..217	CDD:275380	5/23 (22%)
		LRR_8	218..276	CDD:290566	13/58 (22%)
		leucine-rich repeat	218..265	CDD:275380	10/47 (21%)
		LRR_RI	<265..406	CDD:238064	32/144 (22%)
		LRR_8	265..321	CDD:290566	10/56 (18%)
		leucine-rich repeat	266..289	CDD:275380	4/23 (17%)
		leucine-rich repeat	290..313	CDD:275380	5/23 (22%)
		leucine-rich repeat	314..338	CDD:275380	6/27 (22%)
		LRR_8	337..397	CDD:290566	13/60 (22%)
		leucine-rich repeat	339..360	CDD:275380	3/21 (14%)
elfn2	NP_001123827.1	LRR_RI	<55..188	CDD:238064	41/142 (29%)
		leucine-rich repeat	61..81	CDD:275378	4/20 (20%)
		LRR_8	81..140	CDD:290566	17/59 (29%)
		leucine-rich repeat	82..105	CDD:275378	8/23 (35%)
		LRR_4	105..145	CDD:289563	11/40 (28%)
		leucine-rich repeat	106..129	CDD:275378	6/23 (26%)
		LRR_8	128..188	CDD:290566	22/69 (32%)
		leucine-rich repeat	130..153	CDD:275378	8/23 (35%)
		leucine-rich repeat	154..167	CDD:275378	5/13 (38%)
		TPKR_C2	186..229	CDD:301599	12/58 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000