Protein Alignment uex and cnnm2a

DIOPT Version :10

• Sequence 1: NP_001104390.2
• Gene: uex / 5740320
• FlyBaseID: FBgn0262124
• Length: 834
• Species: Drosophila melanogaster
• Sequence 2: NP_001138257.1
• Gene: cnnm2a / 555472
• ZFINID: ZDB-GENE-050208-36
• Length: 811
• Species: Danio rerio
• Alignment Length: 804
• Identity: 356/804 - (44%)
• Similarity: 485/804 - (60%)
• Gaps: 83/804 - (10%)

  Fly    21 TSVDTSNKLLLQKANDFNLSQNLSSSRTRRTI-----ANSFRIVGIRLE--DETVETKNGIPTVL 78
            |:|.|||...|.:|....:...:.||...::|     :....|:|:|||  ||......|...|.
Zfish     6 TAVPTSNMAALNRAGSLTVIFLIVSSCLIKSIDGKDPSEETVIIGLRLEDTDEVSFMDRGFLRVS 70

  Fly    79 VDKEQQFRVFGSGLEENT--AITFTNEKNDYGGPCLKPA-TDLFTPIEVSSNGFSALYSVKF--- 137
            .....:.||:|..:...|  .:.||..:::.....|.|. .....|..:.|:....|.:::.
Zfish    71 ERSRVRLRVYGQNINNETWSKLAFTEHRSNAPAESLSPGDAPASHPCGIRSSDIIILPTMEVNRK 135

  Fly   138 PSFINEFFI--CAKTAEKTTNHSKAATTTP-----------LEHQG-NSDFLKIKTFEPLIPVWL 188
            .|.|.|..:  ..||.:..|.:...|..||           :.|:| ::..:.::..:.|:|.||
Zfish   136 TSGIIELEVKPLRKTEKSKTYYLCTAIGTPGAQDSWSEHTWVYHEGHDTKVIVVEEKKFLLPFWL 200

  Fly   189 AIIIIVTCLGFSALFSGLNLGLMSMDRTELKILRNTGTEKEKKYASKIAPVRDQGNYLLCSILLG 253
            .:|.|...|..|.:|||||||||::|..||:|::|.||||||.||..|.|||.||||||||:|||
Zfish   201 QVIFIAMLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKHYAKAIEPVRSQGNYLLCSLLLG 265

  Fly   254 NVLVNSTFTILLDGLT-SGLFAVIFSTLAIVLFGEITPQAVCSRHGLAIGAKTILVTKTVMAITA 317
            |||||:|.|||||.:. |||.||:.||:.||:||||.|||:|||||||:||.||.:||..|.:|.
Zfish   266 NVLVNTTLTILLDDIAGSGLIAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMILTF 330

  Fly   318 PLSYPVSRILDKLLGEEIGNVYNRERLKELVRVTNDVNDLDKNEVNIISGALELRKKTVADVMTH 382
            |.|||||::||.:||:|||.|||||:|.|::|||:..|||.|.|:|||.||||||.|||.||||.
Zfish   331 PASYPVSKLLDHVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTP 395

  Fly   383 INDAFMLSLDALLDFETVSEIMNSGYSRIPVYDGDRKNIVTLLYIKDLAFVDTDDNTPLKTLCEF 447
            :.|.||:|.||:|||.|:||||.|||:|||||:|:|.:||.||::|||||||.||.|||||:.:|
Zfish   396 LRDCFMISGDAILDFATMSEIMESGYTRIPVYEGERCHIVDLLFVKDLAFVDPDDCTPLKTITKF 460

  Fly   448 YQNPVHFVFEDYTLDIMFNQFKEGTIGHIAFVHRVNNEGDGDPFYETVGLVTLEDVIEELIQAEI 512
            |.:|:||||.|..||.|..:||:|. .|:|.|.||||||:||||||.:|:|||||||||:|::||
Zfish   461 YSHPLHFVFNDTKLDAMLEEFKKGK-SHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEI 524

  Fly   513 VDETDVFVDNRTKTR-RNRYKKADFSAFAERREVQTVRISPQLTLATFQYLSTAVDAFKKDVISE 576
            :||||::.||:||.: .:|.||.|||||........|:|||||.|||.::|:|.|::|....:||
Zfish   525 LDETDLYTDNKTKKKIAHREKKQDFSAFKPTENELRVKISPQLLLATLRFLATEVESFSATQMSE 589

  Fly   577 LILRRLL-NQDVFHNIKTKGKSKDDPSLYIFTQGKAVDFFVLILEGRVEVTIGKEALMFESGPFT 640
            .||.||| :.:|...:|...|.|.....|:|.:.|.||:|:|||:|:|||..|||.:.||:|.|:
Zfish   590 KILLRLLKHPNVIQELKYDDKDKKMSEHYLFHRNKPVDYFILILQGKVEVEAGKEGMKFEAGAFS 654

  Fly   641 YFGTQALVPN----------VVIDSPTQMGSLQ--------------SLNMDSKIR--------- 672
            |:|..:|..:          ||..:.:..||.:              |||...::.
Zfish   655 YYGVLSLTSSPVPLSLSRTFVVSRAESLAGSPENKSPPRPFGLNHSDSLNRSDRMEAVTPTLGSS 719

  Fly   673 --------QSFVPDYSVRAISDVIYITIKRVLYLTAKKATLLEKSRKSG---------TFSSETF 720
                    |.:||||||||:||::||.:.|..|..|..|:.::|:.:|.         || :|..
Zfish   720 NNQLNSFLQVYVPDYSVRAVSDLLYIKVTRQQYQNALMASRMDKTPQSTDSEFTKIELTF-TEHQ 783

  Fly   721 DDEVERLLHSITEN-EKPSCFAQN 743
            |..:|.....:|.| .||:..|.|
Zfish   784 DGPLEESATLLTTNSHKPNHTAHN 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
uex	NP_001104390.2	TlyC	187..>517	CDD:440865	215/330 (65%)
		CAP_ED	<604..>650	CDD:469590	23/45 (51%)
cnnm2a	NP_001138257.1	TlyC	198..>529	CDD:440865	215/331 (65%)