DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34274 and TOM71

DIOPT Version :9

Sequence 1:	NP_001097807.1	Gene:	CG34274 / 5740212	FlyBaseID:	FBgn0085303	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_011985.1	Gene:	TOM71 / 856517	SGDID:	S000001159	Length:	639	Species:	Saccharomyces cerevisiae

Alignment Length:	239	Identity:	56/239 - (23%)
Similarity:	93/239 - (38%)	Gaps:	59/239 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 ELFIYQHPAADESFLKEQPTKVEDVIEYLDVLENANKTDSSKKRQKSTITMDDIKCIVTRRSAVS 90
            |.|..|:  .||:.||:..:          |:..:||....|.::|
Yeast    56 EAFAGQN--EDEADLKDDGS----------VVSGSNKRKKKKNKRK------------------- 89

  Fly    91 TTTFRRGKAKRALINTNQFTFMRQIDSEPDD---RVLAREQREDVAETFRRMGNYEYRKLNFSLA 152
                |..|||    :...|.:....:.|||.   :.|:..||:..|...:..||:.:...||:.|
Yeast    90 ----RNNKAK----SGEGFDYPSLPNGEPDIAQLKGLSPSQRQAYAVQLKNRGNHFFTAKNFNEA 146

  Fly   153 KDYYSKGIQYIKDSPVLYVNRALCFIKLREFKLGIIDCDYVLAKIDEHYLRAWLYRAAAYKRLND 217
            ..||...|:...:.||.|.|.:.|:|...:.: .:|:......:|...:.:|.|.||:|.:.|.:
Yeast   147 IKYYQYAIELDPNEPVFYSNISACYISTGDLE-KVIEFTTKALEIKPDHSKALLRRASANESLGN 210

  Fly   218 --EPNFEYSV-------DRA-------RRFNRSDADFIDEFLDK 245
              :..|:.||       |.|       |..|:.....::|.|.|
Yeast   211 FTDAMFDLSVLSLNGDFDGASIEPMLERNLNKQAMKVLNENLSK 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34274	NP_001097807.1	TPR_11	133..195	CDD:290150	16/61 (26%)
		TPR repeat	133..161	CDD:276809	8/27 (30%)
		TPR repeat	166..197	CDD:276809	7/30 (23%)
TOM71	NP_011985.1	3a0801s09	9..636	CDD:273380	56/239 (23%)
		TPR repeat	127..155	CDD:276809	8/27 (30%)
		TPR repeat	160..190	CDD:276809	7/30 (23%)
		TPR repeat	195..218	CDD:276809	7/22 (32%)
		TPR repeat	345..373	CDD:276809
		TPR repeat	378..406	CDD:276809
		TPR repeat	411..441	CDD:276809
		TPR repeat	446..471	CDD:276809
		TPR repeat	480..508	CDD:276809
		TPR repeat	513..559	CDD:276809
		TPR repeat	564..588	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870