DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34274 and CNS1

DIOPT Version :9

Sequence 1:	NP_001097807.1	Gene:	CG34274 / 5740212	FlyBaseID:	FBgn0085303	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_009713.1	Gene:	CNS1 / 852452	SGDID:	S000000359	Length:	385	Species:	Saccharomyces cerevisiae

Alignment Length:	159	Identity:	44/159 - (27%)
Similarity:	79/159 - (49%)	Gaps:	34/159 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 FMRQIDSEPDD-----------RVLARE-QREDVAETFRRMGNYEYRKLNFSLAKDYYSKGI--- 160
            ||.::| |.|.           :.||.| :..::||.|::.||..|:...|..|::.||||:
Yeast    50 FMTKLD-ETDGAGGENVELEALKALAYEGEPHEIAENFKKQGNELYKAKRFKDARELYSKGLAVE 113

  Fly   161 ---QYIKDSPVLYVNRALCFIKLREFKLGIIDCDYVLAKIDEHYLRAWLYRAAAYKRLNDEPNFE 222
               :.|.:|  ||.|||.|.::|:.::..|.||...|. |:...::.:...:.|:.:||
Yeast   114 CEDKSINES--LYANRAACELELKNYRRCIEDCSKALT-INPKNVKCYYRTSKAFFQLN------ 169

  Fly   223 YSVDRARRFNRSDADFIDEFLD-KMRSLL 250
             .::.|    :|.|.|.::.:| :.:|:|
Yeast   170 -KLEEA----KSAATFANQRIDPENKSIL 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34274	NP_001097807.1	TPR_11	133..195	CDD:290150	24/67 (36%)
		TPR repeat	133..161	CDD:276809	12/33 (36%)
		TPR repeat	166..197	CDD:276809	12/30 (40%)
CNS1	NP_009713.1	3a0801s09	68..>218	CDD:273380	39/140 (28%)
		TPR repeat	83..111	CDD:276809	12/27 (44%)
		TPR repeat	120..150	CDD:276809	12/32 (38%)
		Wheel	257..374	CDD:408742
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910