DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34274 and zgc:123010

DIOPT Version :9

Sequence 1:	NP_001097807.1	Gene:	CG34274 / 5740212	FlyBaseID:	FBgn0085303	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	XP_005169572.1	Gene:	zgc:123010 / 641500	ZFINID:	ZDB-GENE-051120-15	Length:	501	Species:	Danio rerio

Alignment Length:	267	Identity:	47/267 - (17%)
Similarity:	100/267 - (37%)	Gaps:	72/267 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DKKNEHEKPFGLEIPKPELFIYQHPAADESFLKE-QPTKVED-VIEYLD------VLENANKTDS 65
            :::.|.|...|   |..||     ..::||.|:| ..:|||: .:..|:      .|.:.||
Zfish    94 EEEEEEEDDAG---PDSEL-----DESEESELEEVVVSKVEEKPVALLNKSPSGPPLASGNK--- 147

  Fly    66 SKKRQKSTITMDDIKCIVTRRSAVSTTTFRRGKAKRALINTNQFTFMRQIDSEPDDRVLAREQRE 130
            |.::|.:....:|....|......:..:..|.|||                    .:..::|.:|
Zfish   148 SNRQQGARSGEEDPGWDVNSAFVANAVSHIRPKAK--------------------SKGKSKENKE 192

  Fly   131 DVAETFRRMGNYEYRKLNFSLAKDYYS-----KGIQYIKDSPV-------------------LYV 171
            :.:.....:|        ||.||...|     |||:::::...                   .:.
Zfish   193 NESRPAEVIG--------FSEAKTKRSASLVEKGIRFVQEGQYTQAVSLFTEAIKCDPKDYRFFG 249

  Fly   172 NRALCFIKLREFKLGIIDCDYVLAKIDEHYLRAWLYRAAAYKRLNDEPNFEYSVDRARRFNRSDA 236
            ||:.|:..|.::.|.:.|.:..: ::...:.:.:..|.:|...|......|.::::..:.:....
Zfish   250 NRSYCYCCLEQYALALADAEKSI-QMAPDWPKGYYRRGSALMGLKRYSEAEKAMEQVLKLDGDCE 313

  Fly   237 DFIDEFL 243
            :.:::.|
Zfish   314 EAVNDLL 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34274	NP_001097807.1	TPR_11	133..195	CDD:290150	15/85 (18%)
		TPR repeat	133..161	CDD:276809	8/32 (25%)
		TPR repeat	166..197	CDD:276809	6/49 (12%)
zgc:123010	XP_005169572.1	TPR_11	214..276	CDD:290150	9/62 (15%)
		TPR repeat	214..239	CDD:276809	3/24 (13%)
		TPR repeat	244..274	CDD:276809	6/30 (20%)
		TPR_11	250..309	CDD:290150	10/59 (17%)
		TPR_2	279..309	CDD:285020	4/29 (14%)
		TPR repeat	279..307	CDD:276809	4/27 (15%)
		TPR_11	282..343	CDD:290150	5/39 (13%)
		TPR repeat	313..343	CDD:276809	1/8 (13%)
		RRM	<364..>438	CDD:223796
		RRM	370..436	CDD:214636
		zf-CCCH	471..492	CDD:279036
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0548
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900