Protein Alignment: CG34274 and TTC12

• Sequence 1: NP_001097807.1
• Gene: CG34274
• FlyBaseID: FBgn0085303
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: XP_005271661.1
• Gene: TTC12
• HGNCID: 23700
• Length: 777
• Species: Homo sapiens
• Alignment Length: 203
• Identity: 48/204 (24%)
• Similarity: 96/204 (47%)
• Gaps: 30/204 (15%)

  Fly    37 ESFLKEQPTKVEDVIEYLDVLENANKTDSSKKRQKSTI-----------TMDDIKCIVT-RRSAV 89
            :.|||       :|.|..::::..| :|....:||:.:           ..::.:|..| .::.:
Human    10 QKFLK-------NVDEISNLIQEMN-SDDPVVQQKAVLETEKRLLLMEEDQEEDECRTTLNKTMI 66

  Fly    90 STTTFRRGKAKRALINTNQFTFMRQIDSEPDDRVLAREQREDVAETFRRMGNYEYRKLNFSLAKD 154
            |...    .|.::....|...|:..::.:..:|...|.:.:.:|:..:..||..:.:.|:..|..
Human    67 SPPQ----TAMKSAEEINSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAIL 127

  Fly   155 YYSKGIQYIKDSPVLYVNRALCFIKLREFKLGIIDCDYVLAKIDEHYLRAWLYRAAAYKRLNDEP 219
            .||:|::.:||..|||.|||..::||.:::..::||::.| |.||...:|:.:...|...|.:
Human   128 RYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEWAL-KCDEKCTKAYFHMGKANLALKN-- 189

  Fly   220 NFEYSVDR 227
               |||.|
Human   190 ---YSVSR 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34274	NP_001097807.1	TPR_11	133..195	CDD:290150	21/62 (34%)
		TPR repeat	133..161	CDD:276809	8/28 (29%)
		TPR repeat	166..197	CDD:276809	12/31 (39%)
TTC12	XP_005271661.1	TPR_11	106..171	CDD:290150	23/66 (35%)
		BamD	106..>164	CDD:276939	20/58 (34%)
		TPR repeat	106..138	CDD:276939	9/32 (28%)
		TPR repeat	106..134	CDD:276809	8/28 (29%)
		TPR repeat	139..169	CDD:276809	12/31 (39%)
		TPR_11	142..205	CDD:290150	20/60 (33%)
		TPR_1	143..173	CDD:278916	12/31 (39%)
		TPR repeat	174..202	CDD:276809	7/27 (26%)
		TPR repeat	211..236	CDD:276809
		ARM	526..631	CDD:237987
		armadillo repeat	555..591	CDD:293788
		armadillo repeat	597..631	CDD:293788

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E2759_KOG0548
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0003602
OrthoInspector	1	1.000				T608481
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR46540
Phylome	1	0.910		0.750	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.910