DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34274 and ucp7

DIOPT Version :9

Sequence 1:	NP_001097807.1	Gene:	CG34274 / 5740212	FlyBaseID:	FBgn0085303	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_593480.1	Gene:	ucp7 / 2542191	PomBaseID:	SPAC17A5.12	Length:	697	Species:	Schizosaccharomyces pombe

Alignment Length:	241	Identity:	46/241 - (19%)
Similarity:	99/241 - (41%)	Gaps:	64/241 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LTTNTVDKKNEHEKPFGLEIPKPELFIYQHPAA-DESFLKEQPTKVEDVIEYLDVLENANKTDSS 66
            |....:.|:..|:.|...::.:..:...|..:. |||.|          :::|     .:|:|:|
pombe   309 LPKTPIPKRKPHKVPMNEKVSEDRITTNQSRSGNDESSL----------VDFL-----TSKSDNS 358

  Fly    67 KKRQKSTITMDDIKCIVTRRSAVSTTTFRRGKAKRALINTNQFTFMRQIDSEPDDRVLAREQRED 131
            .....|. |.:..:.|:  .:|..:||.|:       :|.|          :|....:.:.:.|.
pombe   359 SFNFPSD-TYEGTENIL--ETAYESTTARQ-------VNNN----------KPGKSTVKKREEET 403

  Fly   132 -------VAETFRRMGNYEYRKLNFSLAKDYYSKGI-----QYIKDSPVLYVNRALCFIKLREFK 184
                   :.|..:..||..:||.:||.|.:.::..:     ::.|..|:| .||:||:.|:.:.|
pombe   404 LNNMVSALVEEQQSTGNELFRKGDFSQAIEEFTNSLSQLPAKHTKRVPLL-SNRSLCYQKVGDLK 467

  Fly   185 LGIIDCDYVL---------------AKIDEHYLRAWLYRAAAYKRL 215
            ..:.|.|.::               ..::::|::..:.:|...::|
pombe   468 TCLQDVDELVDIIGEEKGHGESIRDKSMNDYYVKNMVRKAQVLEQL 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34274	NP_001097807.1	TPR_11	133..195	CDD:290150	19/81 (23%)
		TPR repeat	133..161	CDD:276809	8/32 (25%)
		TPR repeat	166..197	CDD:276809	10/45 (22%)
ucp7	NP_593480.1	UBA	183..218	CDD:279021
		TPR_11	419..479	CDD:290150	18/60 (30%)
		TPR repeat	449..479	CDD:276809	10/30 (33%)
		TPR repeat	500..528	CDD:276809	2/14 (14%)
		PKc_like	<568..638	CDD:304357
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	1	0.960