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Protein Alignment CG34274 and Stip1

DIOPT Version :9

Sequence 1:	NP_001097807.1	Gene:	CG34274 / 5740212	FlyBaseID:	FBgn0085303	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_058017.1	Gene:	Stip1 / 20867	MGIID:	109130	Length:	543	Species:	Mus musculus

Alignment Length:	241	Identity:	52/241 - (21%)
Similarity:	100/241 - (41%)	Gaps:	52/241 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 PKPELFIYQHPAADESFLKEQ--------------------------PTKVEDVIEYLDVLENAN 61
            ||||......|...:..|||:                          ||.:..:.....|  :..
Mouse   209 PKPEPMEEDLPENKKQALKEKELGNDAYKKKDFDKALKHYDRAKELDPTNMTYITNQAAV--HFE 271

  Fly    62 KTDSSKKRQ--KSTITM-----DDIKCIVTRRSAVSTTTFRRGKAKRALINTNQFTFMRQIDSEP 119
            |.|.:|.|:  :..|.:     :|.:.|....:.:..:.|:..|.|.|:...|:.....:   .|
Mouse   272 KGDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHR---TP 333

  Fly   120 D--------DRVLAREQR-----EDVAETFRRMGNYEYRKLNFSLAKDYYSKGIQYIKDSPVLYV 171
            |        :::|..::|     .|:|...:..||..::|.::..|..:|::.|:.......||.
Mouse   334 DVLKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPRDAKLYS 398

  Fly   172 NRALCFIKLREFKLGIIDCDYVLAKIDEHYLRAWLYRAAAYKRLND 217
            |||.|:.||.||:|.:.||:..: :::..:::.:..:|||.:.:.|
Mouse   399 NRAACYTKLLEFQLALKDCEECI-QLEPTFIKGYTRKAAALEAMKD 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34274	NP_001097807.1	3a0801s09	118..>215	CDD:273380	28/109 (26%)
		TPR repeat	133..161	CDD:276809	6/27 (22%)
		TPR repeat	166..197	CDD:276809	13/30 (43%)
Stip1	NP_058017.1	TPR 1	4..37
		3a0801s09	<7..532	CDD:273380	52/241 (22%)
		TPR repeat	7..32	CDD:276809
		TPR repeat	37..67	CDD:276809
		TPR 2	39..71
		TPR repeat	72..100	CDD:276809
		TPR 3	73..105
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	191..233		8/23 (35%)
		Bipartite nuclear localization signal. /evidence=ECO:0000255	222..239		3/16 (19%)
		TPR 4	225..258		4/32 (13%)
		TPR repeat	229..253	CDD:276809	0/23 (0%)
		TPR repeat	258..288	CDD:276809	6/31 (19%)
		TPR 5	260..292		6/33 (18%)
		TPR 6	300..333		5/35 (14%)
		TPR repeat	300..328	CDD:276809	5/27 (19%)
		TPR 7	360..393		7/32 (22%)
		TPR repeat	364..388	CDD:276809	5/23 (22%)
		TPR repeat	393..423	CDD:276809	13/30 (43%)
		TPR 8	395..427		13/32 (41%)
		TPR 9	428..461		4/16 (25%)
		TPR repeat	428..456	CDD:276809	4/16 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Software error:

Can't use an undefined value as an ARRAY reference at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 1034.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-
Hieranoid	0	0.000	Not matched by this tool.