DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG34274 and Stip1

DIOPT Version :10

Sequence 1:NP_001097807.1 Gene:CG34274 / 5740212 FlyBaseID:FBgn0085303 Length:250 Species:Drosophila melanogaster
Sequence 2:NP_620266.1 Gene:Stip1 / 192277 RGDID:621599 Length:543 Species:Rattus norvegicus


Alignment Length:239 Identity:53/239 - (22%)
Similarity:108/239 - (45%) Gaps:31/239 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 PLTTNTVDKKNE--HEKPFGLEIPKPELFIYQHPAADESFLKE-QPTKVEDVIEYLDVLENANKT 63
            |:..:..:.|.:  .||..|.:..|.:.|.......|::  || .||.:..:.....|  :..|.
  Rat   213 PMEEDLPENKKQALKEKELGNDAYKKKDFDKALKHYDKA--KELDPTNMTYITNQAAV--HFEKG 273

  Fly    64 DSSKKRQ--KSTITM-----DDIKCIVTRRSAVSTTTFRRGKAKRALINTNQFTFMRQIDSEPD- 120
            |.:|.|:  :..|.:     :|.:.|....:.:..:.|:..:.|.|:...|:.....:   .|| 
  Rat   274 DYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEERYKDAIHFYNKSLAEHR---TPDV 335

  Fly   121 -------DRVLAREQR-----EDVAETFRRMGNYEYRKLNFSLAKDYYSKGIQYIKDSPVLYVNR 173
                   :::|..::|     .|:|...:..||..::|.::..|..:|::.|:.......||.||
  Rat   336 LKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPRDAKLYSNR 400

  Fly   174 ALCFIKLREFKLGIIDCDYVLAKIDEHYLRAWLYRAAAYKRLND 217
            |.|:.||.||:|.:.||:..: :::..:::.:..:|||.:.:.|
  Rat   401 AACYTKLLEFQLALKDCEECI-QLEPTFIKGYTRKAAALEAMKD 443

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG34274NP_001097807.1 3a0801s09 118..>215 CDD:273380 28/109 (26%)
TPR repeat 133..161 CDD:276809 6/27 (22%)
TPR repeat 166..197 CDD:276809 13/30 (43%)
Stip1NP_620266.1 TPR 1 4..37
3a0801s09 <7..532 CDD:273380 53/239 (22%)
TPR repeat 7..32 CDD:276809
TPR repeat 37..67 CDD:276809
TPR 2 39..71
TPR repeat 72..100 CDD:276809
TPR 3 73..105
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 191..233 4/19 (21%)
Bipartite nuclear localization signal. /evidence=ECO:0000255 222..239 5/16 (31%)
TPR 4 225..258 9/34 (26%)
TPR repeat 229..253 CDD:276809 5/25 (20%)
TPR repeat 258..288 CDD:276809 6/31 (19%)
TPR 5 260..292 6/33 (18%)
TPR 6 300..333 4/35 (11%)
TPR repeat 300..328 CDD:276809 4/27 (15%)
TPR 7 360..393 7/32 (22%)
TPR repeat 364..388 CDD:276809 5/23 (22%)
TPR repeat 393..423 CDD:276809 13/30 (43%)
TPR 8 395..427 13/32 (41%)
TPR 9 428..461 4/16 (25%)
TPR repeat 428..456 CDD:276809 4/16 (25%)
Blue background indicates that the domain is not in the aligned region.

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