DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34274 and sti-1

DIOPT Version :9

Sequence 1:	NP_001097807.1	Gene:	CG34274 / 5740212	FlyBaseID:	FBgn0085303	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001367444.1	Gene:	sti-1 / 178587	WormBaseID:	WBGene00019983	Length:	320	Species:	Caenorhabditis elegans

Alignment Length:	291	Identity:	62/291 - (21%)
Similarity:	115/291 - (39%)	Gaps:	83/291 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 NTVDKKNEHEKPF-----GLEIPKPELFIYQHPAADESFLKEQPTKVEDVIEYLDVLENANKTDS 65
            |...|:.:.||..     .:|:....:..|.:.||  .:.:|:  |..:.:::.:
Worm    13 NAAYKQKDFEKAHVHYDKAIELDPSNITFYNNKAA--VYFEEK--KFAECVQFCE---------- 63

  Fly    66 SKKRQKSTITMDDIKCIVTRRSAVSTTTFRRGKAKRALINTNQFTFMRQID------------SE 118
             |..:....|..|.|.|....|       |.|.|           |.:|.|            ||
Worm    64 -KAVEVGRETRADYKLIAKAMS-------RAGNA-----------FQKQNDLSLAVQWFHRSLSE 109

  Fly   119 PDDRVLAREQRE----------------DVAETFRRMGNYEYRKLNFSLAKDYYSKGIQYIKDSP 167
            ..|..|.::.:|                ::|:..:..||..::|.::..|..:|::.::...::.
Worm   110 FRDPELVKKVKELEKQLKAAERLAYINPELAQEEKNKGNEYFKKGDYPTAMRHYNEAVKRDPENA 174

  Fly   168 VLYVNRALCFIKLREFKLGIIDCDYVLAKIDEHYLRAWLYRAA-------------AYK-RLNDE 218
            :||.|||.|..||.||:..:.|||..: ::|..:::.::.:||             ||: .|..:
Worm   175 ILYSNRAACLTKLMEFQRALDDCDTCI-RLDSKFIKGYIRKAACLVAMREWSKAQRAYEDALQVD 238

  Fly   219 PNFEYSVDRARRFNRSDADFIDEFLDKMRSL 249
            |:.|.:.:..|...||:.:  |....|.|||
Worm   239 PSNEEAREGVRNCLRSNDE--DPEKAKERSL 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34274	NP_001097807.1	TPR_11	133..195	CDD:290150	19/61 (31%)
		TPR repeat	133..161	CDD:276809	6/27 (22%)
		TPR repeat	166..197	CDD:276809	13/30 (43%)
sti-1	NP_001367444.1	3a0801s09	<5..>241	CDD:273380	53/261 (20%)
		TPR repeat	5..33	CDD:276809	4/19 (21%)
		TPR repeat	38..68	CDD:276809	6/44 (14%)
		TPR repeat	80..108	CDD:276809	7/45 (16%)
		TPR repeat	140..168	CDD:276809	6/27 (22%)
		TPR repeat	173..203	CDD:276809	13/30 (43%)
		TPR repeat	208..236	CDD:276809	4/27 (15%)
		STI1	259..311	CDD:407696	4/9 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0548
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810