Protein Alignment kmr and plekha6

DIOPT Version :10

• Sequence 1: NP_001097775.2
• Gene: kmr / 5740131
• FlyBaseID: FBgn0085412
• Length: 3090
• Species: Drosophila melanogaster
• Sequence 2: XP_031751404.1
• Gene: plekha6 / 100036696
• XenbaseID: XB-GENE-958530
• Length: 1245
• Species: Xenopus tropicalis
• Alignment Length: 1468
• Identity: 314/1468 - (21%)
• Similarity: 480/1468 - (32%)
• Gaps: 438/1468 - (29%)

  Fly   294 PGSE----HGTVYIQQNHPNHVVNQACQTQISA-VKPKATP-----SSEESSSNSTKS------- 341
            |.:|    .|....|:.|.:|:.  ..|..::. :..|:.|     |||.|....|..
 Frog    27 PAAETLCSQGPSCSQKCHNDHLA--TVQHSVTVLISRKSGPLWFDMSSETSGKRCTSQVNESSAF 89

  Fly   342 --PSHAPLD-------RKKSAGSIQALKSPITKRPPSTPVTLSGWLHKQGSDGLKVWRKRWFVLA 397
              .|.:||:       |....|.....:|...||.|:..|..:|||:||.|.|:|.|.||||||.
 Frog    90 SMVSDSPLEGSIIRPSRLSKKGIAFGKRSNSMKRNPNAEVMKTGWLYKQASSGVKQWNKRWFVLV 154

  Fly   398 EYCLYYYKGPEEEKLLGSVLLPSYRVSACLPEDKIYRKFAFK--------------------CEH 442
            :.||:|||..:||.:|||:.|.|:.::...|.|.|.||..||                    .||
 Frog   155 DRCLFYYKDEKEEVILGSIPLLSFCIAPVQPSDNISRKHTFKVTVCCIGGVSLNNTAPISRQAEH 219

  Fly   443 QNMRTYWLAADNSEAMMQWVRALAAASLMQAPSSGESEPSVNSSLNHSGENSDSGIHTLQSHPGK 507
            ..:|||:.:|:|.|....|:..:..||.:|..::...|       ....||..|   |....|
 Frog   220 AGIRTYFFSAENREEQESWICVMGEASQVQNLATPRME-------KQDSENIPS---TKDREP-- 272

  Fly   508 GQPTPSSENTGSSGGGSGSGQPLYANAPPKPR----RINDGGYSSPSPEHNEQQQQHPSRRLMSP 568
                    .|.|.|.|.|.|...:.|.....:    ::|..|.....|...:..:..|
 Frog   273 --------ETRSRGEGDGRGSEKFENRSECKQEFLTKVNGRGVPPDRPPDLQPPRHFP------- 322

  Fly   569 TQQLYQQQQHQRSQQQQQQQPQQHHAIYDTRTGH-VSTALQLQQAQQQYSLDHLEAQFQQQQLDM 632
                           :.:|.||.:...:....|. .|||....|.:......|.|...|:|
 Frog   323 ---------------EGEQPPQPNGWGFPPSPGRPASTAFSEGQRRGNLPRTHPEKVAQRQ---- 368

  Fly   633 EEQIARLQQ----QRAAEEIYGEREMYMAKLMQQRQGPNGTYPTQQQLLQAERRTPDAYGRSKQQ 693
             ..:::|||    :|||                   ||.....:..:.....||.|:.|.:...|
 Frog   369 -NSMSQLQQWVNLRRAA-------------------GPTEEIQSPSRFFSESRRIPECYSQCPSQ 413

  Fly   694 RL----FAAAAAAADYEDIYNMSQLAGGGGVPMSAQEALLQ--------------EAASYRRPLS 740
            .|    :.::.|.:..:.|.:|...  ..|||....|...|              ||.||.|
 Frog   414 YLDGYQYYSSPAGSRPDSICSMPIF--DRGVPQWGAEDKRQIHHKLVPYYPRDWNEAGSYGR--- 473

  Fly   741 PPSYDGSKHVPAMPQRYTPNHLEASAADQLINTMDLRARTAAAIVRPHSADFLEYEARAEAAAAA 805
                .....||. ||.|   :.|..||.:.:..:.|:.| :.::.|.:|.....|
 Frog   474 ----QTEMWVPC-PQLY---YQETDAACESLRHLSLQPR-SRSVPRSNSQGTYNY---------- 519

  Fly   806 AAAAVAQSQQESGRAPR-------PKSSLDINRTPDSFYYSEASYADKMRKSALYLQSGGAGAAQ 863
                         ..||       |.:..| ..|.:..:...|:|.  ||:|....:.|..|...
 Frog   520 -------------TRPRVYSPVRSPSARFD-GVTREDIFGDPAAYT--MRRSVSSPKYGYIGDRH 568

  Fly   864 PQQPGSYRTT---------------------GADF-----------NSGVNTI------------ 884
            |.|.|.|..:                     ..||           .|.||.:
 Frog   569 PHQAGVYSYSYPASPPLHDKMDEMLDLQLQRHLDFLDQQMSESETLISMVNNMVHSSPRAQIFMQ 633

  Fly   885 --GYENPYERA---YKRQE-----LLAEAQGGGASSMPRMSRSASQGRSVASQLQSPQQEDLPPL 939
              .|.:||..|   ||..|     ||.:.              ..|.::|..|.:..||     |
 Frog   634 VSPYSDPYREALQSYKINEHDTDKLLGQL--------------CEQHKAVREQDRLVQQ-----L 679

  Fly   940 NVHPGSIFPPSMSTQEIISKNEQFLRSAS--ARLPKRSGGMDDDYSAGNSTTTSPTGGAGASNSP 1002
            .....|:....|.|.:   :.|.|....:  ..|..|...:.:...:.....:..|.....|:..
 Frog   680 RAEKESLESALMGTHQ---EMEMFGNQTAFPENLLHRKESLQNQLISIRVELSQATTALNNSSLE 741

  Fly  1003 QHNLDGERKREESMKRLLE--WKQRML--QSPLTRKGIQQG----GSNMSAMSKLGSNPNILLAS 1059
            ...|:||      :..|.:  |:|..|  |:.|..:.||:.    ...|..:.|  :||:
 Frog   742 YEALEGE------VSALHDTLWEQLNLNIQNELMNRQIQREIWRIQDVMEGLRK--NNPS----- 793

  Fly  1060 TAVASGARYAPQAGKTVLVGNGNGTAQGAGNP-PSASGIQRSRSESQANVGPGGVVYNNYSSDDE 1123
                                .|..||:....| |||:                      :||:..
 Frog   794 --------------------RGTDTAKHRVLPGPSAT----------------------FSSNSP 816

  Fly  1124 AGTVDDDNLYSATAG---RSSSSKTTTKATTSQ-AIVATTTAALAITNLGS-SKNLETPNQTETE 1183
            |..:...:|.|..:.   .|.|..:.||.|||: :........|:.|.|.| |..|..|.:...:
 Frog   817 ASPISSASLTSPLSPFSLISGSQGSPTKQTTSEDSGPPRPPLPLSYTPLDSPSDVLPLPGEGCFQ 881

  Fly  1184 ATP-SSSSTASSTKAKFQLKPILKVHEASKTRIIQVQPKHLEERPKLR-LQLPKAMGNEEEQKQE 1246
            ..| ..||....::.|..|:|.       |...:|:......||  || ||..        .:.|
 Frog   882 PWPYPLSSCWLHSELKMNLEPY-------KRESLQLSSSLTPER--LRSLQFC--------SEHE 929

  Fly  1247 DEEQENVEAE---PVPILPKKTAPKSPQNANYVPVYNNKLVSNYENMEFGKPIPESKIPHSNAAI 1308
            .|:|:.|..:   .|.|:|..|...:...:...|....:..|...|....:..|:|.:
 Frog   930 SEKQQQVPLQVINKVGIVPPITKSHNEDESEMKPSVVRREGSRTPNGNISRERPKSAL------- 987

  Fly  1309 TDPEETPMLMQLKLFKEQQDQQKQQQENEEEDLTPTAESKPIPGEEDMGAPKVIKDQKLESNEEE 1373
             .|.|....|.:   :||.|:.|:.|       |.:.:.|.             :..:|.:|::.
 Frog   988 -FPSEVKSKMSV---EEQNDRMKRHQ-------TGSVKEKR-------------RSLQLLANQQS 1028

  Fly  1374 QELEDEDDST--------ACEEYTDDDIDEALAQDDEDEAVVEAVESQELAEERELQQIYVNEPI 1430
            :....:...|        :..|....|: ||:.:..|.:...|:.: .|:|..|:::       :
 Frog  1029 EHSATKSTGTYRIVRRHRSVHEVDISDL-EAVLRSQEPQHTYESPQ-DEIARLRKME-------V 1084

  Fly  1431 TPTDQQFDESHYLPM-----TPKKV-------ELGQPGVLTLVSATYAEEEEENHYVEMTKGIQD 1483
            .|.....|.:..||:     ||:||       ||...|.|     :..|.:|:...||..|.:..
 Frog  1085 EPQSYSVDITRELPVPDKLSTPEKVLIPERYIELEPEGPL-----SPEEMQEKRRKVERIKTLIA 1144

  Fly  1484 EDCRSNYEIMCLASTSSSAFKVTTKTEPVYMELAGVKASSAVPATEEAHCSSGRSTLKKCKKSGT 1548
            :....|     :...|.|..:||...|....|.......|...|.|.:.  .||.....|.....
 Frog  1145 KSSLQN-----VIPLSDSELEVTPDPESQLQEQEKRIELSCTLAAEASR--RGRLLSALCATPSP 1202

  Fly  1549 ETLKKKTKKRQGKDMPDIL--KPAKSALALASDSSDAD 1584
            .|..|       ...|..|  .|..|||...:.|..:|
 Frog  1203 PTSPK-------SPAPQTLSSSPEHSALGGGNSSRSSD 1233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kmr	NP_001097775.2	PH_PEPP1_2_3	366..469	CDD:270068	46/122 (38%)
plekha6	XP_031751404.1	PH_PEPP1_2_3	123..246	CDD:270068	46/122 (38%)
		PHA03377	<240..>580	CDD:177614	88/445 (20%)