Protein Alignment CAMK1D and CG10177

DIOPT Version :10

• Sequence 1: NP_705718.1
• Gene: CAMK1D / 57118
• HGNCID: 19341
• Length: 385
• Species: Homo sapiens
• Sequence 2: NP_651150.1
• Gene: CG10177 / 42772
• FlyBaseID: FBgn0039083
• Length: 411
• Species: Drosophila melanogaster
• Alignment Length: 271
• Identity: 71/271 - (26%)
• Similarity: 132/271 - (48%)
• Gaps: 10/271 - (3%)

Human    17 EDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIK-HEN 80
            |.|:...|..|.:.....:.:...:.:|......||.:.|:...........|..|||::: |.|
  Fly   143 EAIQLYIETIEPVEHNTRTLIYRGQTRANRTKCTVKMVNKQTQSNDRGDTYMEAEVLRQLQSHPN 207

Human    81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVEK-GFYTEKDASTLIRQVLDAVYYLHRMGIVHRD 144
            |:.|....|...::|.|::.:...  ..::::| |..:|.||.:::|..:.|:.::|::.::|||
  Fly   208 IIELMYTVEDERYMYTVLEHLDCN--MQKVIQKRGILSEADARSVMRCTVSALAHMHQLQVIHRD 270

Human   145 LKPENLLYYSQDEE---SKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWS 206
            :||||||..|...:   ..:.:::|.|:... :|..:...||||.|:|||::|...|...||.||
  Fly   271 IKPENLLVCSSSGKWNFKMVKVANFDLATYY-RGSKLYVRCGTPCYMAPEMIAMSGYDYQVDSWS 334

Human   207 IGVIAYILLCGYPPFYD--ENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYT 269
            :||..:.:|||..||..  :|..:::..|:.....:.......:|..|...|..|:..||:.|..
  Fly   335 LGVTLFYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLLVSDPSYRVP 399

Human   270 CEQAARHPWIA 280
            ..:..:..::|
  Fly   400 IAELDKFQFLA 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAMK1D	NP_705718.1	STKc_CaMKI_delta	12..312	CDD:271070	71/271 (26%)
		Autoinhibitory domain. /evidence=ECO:0000250	279..319		1/2 (50%)
		Calmodulin-binding. /evidence=ECO:0000250	299..320
		Nuclear export signal. /evidence=ECO:0000250	318..324
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	360..385
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	66/247 (27%)