Protein Alignment PRSS8 and tpr

DIOPT Version :10

• Sequence 1: NP_002764.1
• Gene: PRSS8 / 5652
• HGNCID: 9491
• Length: 343
• Species: Homo sapiens
• Sequence 2: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 263
• Identity: 93/263 - (35%)
• Similarity: 140/263 - (53%)
• Gaps: 32/263 - (12%)

Human    33 AEAPCGVAP-QARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAY 96
            ::..||:|. |.||.||......|:||...:.|.|...|..||:::|::|:|:||... ..||..
  Fly   114 SDCVCGIANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYG-FRKERI 177

Human    97 EVKLGAHQLDSYSEDAKVSTLK-------DIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPIC 154
            .|:|..|       |.|:|.::       ::|.||.|.......|||:::|..|:.|:..:.|:|
  Fly   178 SVRLLEH-------DRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVC 235

Human   155 LPAANASF--PNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFV 217
            :|....||  .||:   |||||  |..|...|...||:::||::|::.|.       |....:.:
  Fly   236 MPTPGRSFKGENGI---VTGWG--ALKVGGPTSDTLQEVQVPILSQDECR-------KSRYGNKI 288

Human   218 QEDMVCAGYVEGGKDACQGDSGGPLSCPVEGL--WYLTGIVSWGDACGARNRPGVYTLASSYASW 280
            .::|:|.||.|||||:|||||||||.....|.  ..:.|:||||:.|.....||||...:.|.:|
  Fly   289 TDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTW 353

Human   281 IQS 283
            |::
  Fly   354 IKN 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRSS8	NP_002764.1	Tryp_SPc	45..284	CDD:238113	88/250 (35%)
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	88/248 (35%)