Protein Alignment PRSS8 and CG11911

DIOPT Version :10

• Sequence 1: NP_002764.1
• Gene: PRSS8 / 5652
• HGNCID: 9491
• Length: 343
• Species: Homo sapiens
• Sequence 2: NP_608518.1
• Gene: CG11911 / 33206
• FlyBaseID: FBgn0031249
• Length: 277
• Species: Drosophila melanogaster
• Alignment Length: 293
• Identity: 83/293 - (28%)
• Similarity: 135/293 - (46%)
• Gaps: 44/293 - (15%)

Human    15 VAILLYLGLLRSGTGAEGAEAPCGVAPQ---ARITGGSSAVAGQWPWQVSIT---YEGVHVCGGS 73
            :.:.|.:.|:.:..||:.::....:.|.   ..:..|:.|.....|:.||:.   .:..|:|||:
  Fly     4 ITVTLVIALVAAAQGAKLSDKLAKLVPSFATGFVINGTEAEPHSAPYIVSLATNYLKHSHICGGT 68

Human    74 LVSEQWVLSAAHCFPSEHHKEAYEVKLGAH---QLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDI 135
            |:::.|:::||||. ||  .....:..|.|   ::|..::..:|...:   .|..|.......||
  Fly    69 LINKDWIVTAAHCI-SE--PVGMSIIAGLHTRAEVDELTQQRQVDFGR---VHEKYTGGVGPYDI 127

Human   136 ALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLT-PKPLQQLEVPLISRE 199
            |||.::....|:.:::|..||:.........|  :.|||.  |...:.: .|.||.:...:::.|
  Fly   128 ALLHVNESFIFNEWVQPATLPSREQVHEGETH--LYGWGQ--PKSYIFSGAKTLQTVTTQILNYE 188

Human   200 TCNCLYNIDAKPEEPHF--VQEDMVCAGYVEGGKDACQGDSGGPL-----SCPVEGLWYLTGIVS 257
            .|        |.|.|..  :.|..:|:..::..|.||.|||||||     :.|.|    |.||||
  Fly   189 EC--------KEELPESAPIAESNICSSSLQQSKSACNGDSGGPLVVEFTNAPSE----LIGIVS 241

Human   258 WG-DACGARNRPGVYTLASSYASWIQSKVTELQ 289
            || ..||..|.|.:||..|:|..||    |.:|
  Fly   242 WGYIPCGLANMPSIYTKVSAYIDWI----TNIQ 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRSS8	NP_002764.1	Tryp_SPc	45..284	CDD:238113	76/253 (30%)
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	74/250 (30%)