Protein Alignment MAPK3 and p38a

DIOPT Version :10

• Sequence 1: NP_002737.2
• Gene: MAPK3 / 5595
• HGNCID: 6877
• Length: 379
• Species: Homo sapiens
• Sequence 2: NP_477163.1
• Gene: p38a / 42866
• FlyBaseID: FBgn0015765
• Length: 366
• Species: Drosophila melanogaster
• Alignment Length: 337
• Identity: 161/337 - (47%)
• Similarity: 226/337 - (67%)
• Gaps: 12/337 - (3%)

Human    42 YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHENVIGIRD 105
            |..||.:|.||||.||.|........|||||:: ||:...:.:||.||:::|....||||||:.|
  Fly    25 YQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLD 89

Human   106 ILRA----STLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRD 166
            |...    .:||..:.||:|..||:.||..:::.|.||:||:.:.:|||||||||||||.|:|||
  Fly    90 IFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDHVQFLVYQILRGLKYIHSAGVIHRD 154

Human   167 LKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSV 231
            |||||:.:|..|:|:|.||||||..:.|      :|.|||||||||||||||...|.:::|||||
  Fly   155 LKPSNIAVNEDCELRILDFGLARPTENE------MTGYVATRWYRAPEIMLNWMHYDQTVDIWSV 213

Human   232 GCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLF 296
            |||:||:::.|.:|||..::.|||.|:.:||:|..|.|..|.:..||:|:||||.....::..:|
  Fly   214 GCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQSLPPMKGRSFKNVF 278

Human   297 PKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLK 361
            ..::..|:|||::||..:..||||.||||:|||||:|.:|:.|..: .|:..:.|..|||.::.|
  Fly   279 KNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVEQTS-PPYDHSFEDMDLPVDKWK 342

Human   362 ELIFQETARFQP 373
            |||::|...|:|
  Fly   343 ELIYKEVTNFKP 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK3	NP_002737.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26
		STKc_ERK1_2_like	36..370	CDD:270839	159/332 (48%)
		TXY	202..204		1/1 (100%)
p38a	NP_477163.1	STKc_p38	9..354	CDD:143356	160/335 (48%)