Protein Alignment MAPK3 and Erk7

DIOPT Version :9

• Sequence 1: NP_002737.2
• Gene: MAPK3 / 5595
• HGNCID: 6877
• Length: 379
• Species: Homo sapiens
• Sequence 2: NP_001188568.1
• Gene: Erk7 / 31877
• FlyBaseID: FBgn0052703
• Length: 916
• Species: Drosophila melanogaster
• Alignment Length: 390
• Identity: 135/390 - (34%)
• Similarity: 199/390 - (51%)
• Gaps: 89/390 - (22%)

Human    27 EVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI-SPFEHQTYCQRTLREIQ 90
            |::......|||..|      :|:||||:|..|.|...|..||:||: ..|..:|..|||.||:.
  Fly    16 ELDQTVESIFDVRKR------MGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVI 74

Human    91 ILLRFR-HENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQLSND-HICYFLYQILRG 153
            .|..|| |.|::.:.||.:||.   ..|.|:|.:.||:||:.::|...:..| |..:.:||::..
  Fly    75 FLRAFRCHPNIVRLVDIFKASN---NLDFYLVFEFMESDLHNVIKRGNVLKDVHKRFVMYQLINA 136

Human   154 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIA-------DPEHDHTGFLTEYVATRWYR 211
            :|:|||.||:||||||||:||::.|.||:.||||||..       |.|.|  |.||:||||||||
  Fly   137 IKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQD--GMLTDYVATRWYR 199

Human   212 APEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMK 276
            ||||::.|:.|||.||:|.:||||.||:..:|:|.|...::|:..|
  Fly   200 APEILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKI------------------- 245

Human   277 ARNYLQSLPSKTKVAWAKLFPKSDS------------------------KALDLLDRMLTFNPNK 317
                :.|||:.||:..|.:.|...|                        ..:.|:..:|..||:.
  Fly   246 ----VTSLPNVTKLDIASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHN 306

Human   318 RITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLP-------------KERLKELIFQETA 369
            |:|.:||:.|||:.::...:.|        ..:.:|.:|             :..|.|||.:||:
  Fly   307 RLTAKEAIRHPYVSRFQYASAE--------MDLHMDVVPPLKDHVRYDVDQYRNSLYELIDRETS 363

Human   370  369
              Fly   364  363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK3	NP_002737.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26
		STKc_ERK1_2_like	36..370	CDD:270839	134/381 (35%)
		TXY	202..204		1/1 (100%)
Erk7	NP_001188568.1	STKc_MAPK15-like	17..358	CDD:270841	130/382 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D741207at2759
OrthoFinder	1	1.000	-	-		FOG0000164
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820