Protein Alignment SLC39A4 and Zip99C

DIOPT Version :8

• Sequence 1: NP_570901.3
• Gene: SLC39A4 / 55630
• HGNCID: 17129
• Length: 647
• Species: Homo sapiens
• Sequence 2: NP_001189313.1
• Gene: Zip99C / 43533
• FlyBaseID: FBgn0039714
• Length: 355
• Species: Drosophila melanogaster
• Alignment Length: 350
• Identity: 98/350 (28%)
• Similarity: 156/350 (45%)
• Gaps: 74/350 (21%)

Human   327 YLYGSLATLLICLCAVFGLLLLTCTGCRGVTHY-------ILQTFLSLAVGAVTGDAVLHLTPKV 384
            :::..|.:::|.|..:|.|:::..........|       :|:..||.|||.:.||..|||.|:
  Fly    36 WVFSLLGSVVIGLSGIFPLIIIPTEEKMAKEGYKDPADSKLLRVLLSFAVGGLLGDVFLHLLPE- 99

Human   385 LGLHTHSEEGLSPQPT---------WRLLAMLAGLYAFFLFENLFNLLLPRD-----PEDLEDGP 435
                  :.||.:..|:         |    :|:|:..|.:.|.:|:.....|     |:.:|...
  Fly   100 ------AWEGDNQDPSSHPSLRSGLW----VLSGILIFTIVEKIFSGYASADEENPQPKCVEIAN 154

Human   436 CGHSSHSHGGHSHGVSLQLAPSELRQPKPPHEGSRADL----------VAEESPELLNPEPRRLS 490
            |  ....|||       ||...|..:..    |...|:          ..|:..:....:|::::
  Fly   155 C--LLRRHGG-------QLPEGETSESC----GGACDIEDVGKVCFLREQEQKSKERKEQPKKVA 206

Human   491 PELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSV 555
            ..|.|      |.:::.||..||||..:|..|::.|:..:.|:..||:|||:||||.||.:|.|.
  Fly   207 GYLNL------LANSIDNFTHGLAVAGSFLVSFRHGILATFAILLHEIPHEVGDFAILLRSGFSR 265

Human   556 RQALLLNLASALTAFAGLYVALAV----GVSEESEA---WILAVATGLFLYVALCDMLPAMLKVR 613
            ..|.   .|..|||.|||..||..    ||:...||   ||:....|.||::||..:||.:||..
  Fly   266 WDAA---RAQLLTAGAGLLGALVAIGGSGVTSAMEARTSWIMPFTAGGFLHIALVTVLPDLLKEE 327

Human   614 DPR---PWLLFLLHNVGLLGGWTVL 635
            :.:   ..||.|:..:.|:...|:|
  Fly   328 ERKESIKQLLALVFGIALMAVMTML 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC39A4	NP_570901.3	None
Zip99C	NP_001189313.1	Zip	34..350	CDD:280666	96/347 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG0428
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D657777at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910