Protein Alignment ETNK2 and CG2201

DIOPT Version :10

• Sequence 1: NP_001284689.1
• Gene: ETNK2 / 55224
• HGNCID: 25575
• Length: 394
• Species: Homo sapiens
• Sequence 2: NP_724349.1
• Gene: CG2201 / 35417
• FlyBaseID: FBgn0032955
• Length: 554
• Species: Drosophila melanogaster
• Alignment Length: 307
• Identity: 69/307 - (22%)
• Similarity: 117/307 - (38%)
• Gaps: 111/307 - (36%)

Human   109 VLVRVYGER----------TELLVDRENEVRNFQLLRAHSCAPKLYCTFQNGLCYEYMQGVALEP 163
            ||:|:||:.          ||.:|        |.||...:..|||:..|..|...:|:...||..
  Fly   189 VLLRIYGQTHGDHALESMITESVV--------FALLSERNYGPKLHGIFPGGRIEQYIPARALTT 245

Human   164 EHIREPRLFRLIALEMAKIHTIHANGSLPKPILWHKMHNYFTLVKNEINPSLSADVPKVEVLER- 227
            ..:.|.|:.:.:|.:|.:||:::...|.....:|:.|..:.:.:::.:|.|:..: .|..||::
  Fly   246 AELGEQRILKRVAEKMGEIHSLNIPMSKEPDWIWNCMQRWVSGLESIVNGSVQTN-QKSSVLKKQ 309

Human   228 -----------ELAWLKEHLSQLESPVVFCHNDLLCKNIIY------------------------ 257
                       |:||::..:.:.:.|||||||||...||:.
  Fly   310 MELMRTFDYVQEMAWIRSIIDEGDYPVVFCHNDLQEGNILMRQPSAGQNERTPRESISSLRSNFD 374

Human   258 ----DSIKGH-----------------------------------------VRFIDYEYAGYNYQ 277
                ||:.|:                                         :..||:||..|||:
  Fly   375 ETLGDSLDGNSNISDTETHKSRSVSPSPCPELDTTNDSALDSSFMADNEPDLIIIDFEYCAYNYR 439

Human   278 AFDIGNHFNEFAGVNEVDYCLYPARETQLQWLHYYLQAQKGMAVTPR 324
            .:|:.|||.|:.    .||       |..|:.::|..:.....|..|
  Fly   440 GYDLANHFIEWT----FDY-------TNPQFPYFYHNSSNCATVQQR 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ETNK2	NP_001284689.1	ETNK_euk	83..338	CDD:270706	69/307 (22%)
CG2201	NP_724349.1	ChoK_euk	159..549	CDD:270705	69/307 (22%)