DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment larp and ssb-1

DIOPT Version :9

Sequence 1:	NP_001247347.1	Gene:	larp / 53567	FlyBaseID:	FBgn0261618	Length:	1673	Species:	Drosophila melanogaster
Sequence 2:	NP_491411.1	Gene:	ssb-1 / 172070	WormBaseID:	WBGene00016653	Length:	396	Species:	Caenorhabditis elegans

Alignment Length:	264	Identity:	58/264 - (21%)
Similarity:	107/264 - (40%)	Gaps:	72/264 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   719 AAYIELDANSIKEAIKKQVEYYFSVDNLTGDFFLRRKM-DPEGYIPVTLIASFHRVLALTTDVAV 782
            ||.:..||:   :.|.||:||||...||..|.||:.|: :.:|::|:|.:.:|:|:.:::.|...
Worm     5 AAAVHDDAD---QKIIKQLEYYFGNINLPRDKFLQEKLKEDDGWVPITTMLNFNRLASISKDTEK 66

  Fly   783 IVNAIKES------------------------DKLELFEGYKVRT---KTTPTTWPITEVPE-VN 819
            |.||:|.|                        :.||.::..|.||   |...|...:.::.: .|
Worm    67 IANAVKNSGSGIISVSEDNQKIRRNEENPVPENSLEYWQKIKHRTVYMKGFSTDTQLDDIIQWAN 131

  Fly   820 E-GEPKAIGTLEQEQLEQNDG--------QEKLEEQTEADSPPPILTSAMATKPLNSIPPPPMPR 875
            : ||.:   .:...:|:..|.        ..|..|:.||.....:                   :
Worm   132 QFGETE---NVLMRRLKPGDRTFKGSVFITYKTREEAEAAQKAEV-------------------K 174

  Fly   876 NPQNLVPKMLQDK---------QQSRSSTIAALNSVNAISALTQQVEGGAAELAGHLSGLAESVK 931
            ..:..:.||:||:         :::|::..||.::.|...|:..:....|......|....:.:.
Worm   175 FGETELTKMMQDEYWTLKNKETKEARAANKAAKSAKNTSEAIESEKAQHAVRYEKGLILAVDGLG 239

  Fly   932 PKST 935
            |.||
Worm   240 PDST 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
larp	NP_001247347.1	LARP_1_2	730..803	CDD:153403	27/97 (28%)
		DM15	1341..1382	CDD:128927
		DM15	1383..1421	CDD:128927
ssb-1	NP_491411.1	LARP_3	9..90	CDD:153397	26/83 (31%)
		RRM1_La	111..183	CDD:240737	12/93 (13%)
		RRM_3	230..328	CDD:285930	4/14 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900