Protein Alignment: larp and larp1b

• Sequence 1: NP_001247347.1
• Gene: larp
• FlyBaseID: FBgn0261618
• Length: 1673
• Species: Drosophila melanogaster
• Sequence 2: NP_001121461.1
• Gene: larp1b
• XenbaseID: XB-GENE-5737452
• Length: 991
• Species: Xenopus tropicalis
• Alignment Length: 1291
• Identity: 394/1292 (30%)
• Similarity: 539/1292 (42%)
• Gaps: 424/1292 (33%)

  Fly   292 QPKAQQQQQQTKQTASQNNNAQNTASNKKTQQQQQPQQGATTTTQTTTAAAAAATAAAAATAATT 356
            :|:...:....|:.....::.|.:|  .||.:..||:....|..|:
 Frog    22 RPQKPDENNSNKENTKGQSSCQMSA--HKTVEAPQPRVNPWTKKQS------------------- 65

  Fly   357 SAAAATSSAAAVPAATTETATTTTV---DASQADALAKVVVKDKKKVNQKASDFSNVGDWPTLIG 418
                              .||..||   |.......|| |::..|..::|.|||.::.:|||
 Frog    66 ------------------LATNNTVYFHDHQGQQGTAK-VIRAGKPPSKKTSDFHDITNWPT--- 108

  Fly   419 GTSGSGKATSNEPKRNPTKKQQSAKTAAA--VAASSNTTSSEVATE-SNVAGTTSSSNSNPSSST 480
                        |........|:...|||  .|||....||:..|: .:|..|..:.|    ...
 Frog   109 ------------PSEIANHGTQNVLCAAANGKAASKQEKSSDGKTDHKDVCETKENCN----MEV 157

  Fly   481 TTTNTTTNSQATTAPVASTSHDAKAQRDAEPAANSAAGTTGTAAGPALTKKIPKHKWRPLPIDLA 545
            ...|...|.|.          :|.||:                      ||..|.||.||.|:..
 Frog   158 QVKNPKPNDQV----------EATAQK----------------------KKFNKQKWMPLHIEET 190

  Fly   546 KSSRPKPIGGRPNRRFSDDIADQRRPPRVYHDRQPGAGGAGVESRHPHAGRHPYGSRPATATSER 610
            |:.:                   :..|.::.:    :......||:.::.:..|
 Frog   191 KTVK-------------------QESPTIHKN----SSSQCEVSRNQNSKQRDY----------- 221

  Fly   611 VDSWRSSSSTTTAAFDEQRSGAAGGAGAAGTGVGSATRGPRRYRTPYRGGRQGRGGFSRQGPGRP 675
              |||..   .....||..|..:.|....|:               .||..:|||    :|.|||
 Frog   222 --SWRLD---RRRELDEVSSVHSEGGNIRGS---------------LRGSGRGRG----RGRGRP 262

  Fly   676 ----TYRIPRHLLASGEYANYLPADAAGADSQSSYVLMGT--HYFGNVPAAYIELDANSIKEAIK 734
                :|....:.:.:....||        .|...|...||  |.:        .:|...:||.:|
 Frog   263 YMHYSYSARENRMRTDHIENY--------KSMMYYYDDGTGMHVY--------PVDKKLLKEYLK 311

  Fly   735 KQVEYYFSVDNLTGDFFLRRKMDPEGYIPVTLIASFHRVLALTTDVAVIVNAIKESDKLELFEGY 799
            :|:|||||.:||..|||||||||.:|::|::|||.|:||.:|||||.::..|:|:|.::|:.: .
 Frog   312 RQIEYYFSTENLEKDFFLRRKMDLQGFLPLSLIAGFYRVQSLTTDVDLMCEALKDSVEVEIVD-Q 375

  Fly   800 KVRTKTTPTTWPITEVPEVNEGEPKAIGTLEQEQLEQNDGQ-----------EKLEEQTEADSPP 853
            |:|.|..|..|||...|.::              |.:.|..           :|||..|
 Frog   376 KIRRKVDPEKWPIPSAPSLD--------------LTRTDFSRFIDCPEFIPGKKLESHT------ 420

  Fly   854 PILTSAMATKPLNSIPPPPMPRNPQNLVPKMLQDKQQSRSSTIAALNSVNAISALTQQVEGGAAE 918
                        .|:|..|...      ...|||          ..|.:|.:.::
 Frog   421 ------------GSVPNSPRKE------CSFLQD----------GSNKLNNLQSM---------- 447

  Fly   919 LAGHLSGLAESVKPK--STSTPDKRNAASAGNGAGSAAALVAEPEGIWKEVKRRSKTNAIKENAT 981
                         ||  |:|.|:                |.:||   |.|||:|.:.:.|
 Frog   448 -------------PKVLSSSMPE----------------LDSEP---WIEVKKRRRPSPI----- 475

  Fly   982 TPPQQQQPPLSQTLNNNNDNVKTNNTSSKSKSSSNNAPSNASSSATVCVTTNNASSATKATTKTT 1046
                                          ||...:.|:..:|...:|
 Frog   476 ------------------------------KSKEPDIPTQITSKPQLC----------------- 493

  Fly  1047 TTSTATTTTNNNIKSGNAAYSKTHSKSSSKTAAPPSAQCHAEKEELDFQFDEELMDPLPPGTGRI 1111
                                                  ...:.|:|||.|||||...    .||.
 Frog   494 --------------------------------------DEPDPEDLDFMFDEELQHM----QGRK 516

  Fly  1112 NNFTENFSDDDESDYEFADRDINKLLIVAQV-GRAPKHEGYDRTADFTSRTKITQDLENIINDGL 1175
            |.||: :|||| ||||..|:|:||::||.|. ....||.|.|||.:..||.|:|.:|..:|||||
 Frog   517 NTFTD-WSDDD-SDYEIDDKDLNKIIIVTQTPPHLKKHPGGDRTGNHISRAKMTSELAKVINDGL 579

  Fly  1176 VNYEEDLW---------TTTNVVADYKTVNVISQADFEKLAG----GRNKSVLPPQVVPPPPPFE 1227
            ..||:|||         .:...:..::.:|:||:.:|:.||.    .:|....|..:    |.|:
 Frog   580 YYYEKDLWMDCEEQNYVPSKQELEHFRKLNLISKEEFDNLAPEFQIEQNLEQSPLNI----PTFQ 640

  Fly  1228 EDLDETLVGDTTLN-----------STLNNTLKSRRA----------RFY-AAPNSHSIDPRTPR 1270
            :...|...|..|..           |....|.||.|.          ||| ....:.|||.::||
 Frog   641 QVCCEDFHGPATTQFHPTDVQQSPMSCHARTPKSPRTPRLKDPSKTPRFYPVVKEARSIDVQSPR 705

  Fly  1271 KRKLRHTANPPVEAHVGWLLDTVEHRPRTTSMGSS-AGTSPTASSYGSFGSSVPQSLPVFQHPSH 1334
            |||.||:.|||:|.||||::|:.||||||:|:.|| |..|..|...||:|.: |.|||.||||||
 Frog   706 KRKTRHSTNPPLEYHVGWVMDSKEHRPRTSSVSSSNASPSEVAPLTGSYGCT-PHSLPKFQHPSH 769

  Fly  1335 ALLKENNFTQQAYHKYHSRCLKERRRLGYGQSQEMNTLYRFWSFFLRENFNKSMYNEFRSLALED 1399
            .|||||.||||.||||..|||.||::||.|||.||||||||||||||::|||.||.|||.||:|:
 Frog   770 ELLKENGFTQQVYHKYRRRCLNERKKLGVGQSPEMNTLYRFWSFFLRDHFNKKMYEEFRQLAVEE 834

  Fly  1400 AGNGFRYGLECLFRFFSYGLEKKFRPNIYQDFQDETIADYETGQLYGLEKFWAFLKYYKNGEKLE 1464
            |...:||||||||||:|||||:|||..:::|||:||:.|||.|||||||||||:|||.| .:.|.
 Frog   835 AKENYRYGLECLFRFYSYGLERKFRQELFEDFQEETVKDYEHGQLYGLEKFWAYLKYSK-AKNLS 898

  Fly  1465 VQPKLAEYLKSFKNIEDFRVVEP--EINEMLQGVGSLNPGRQLNRHRSVSESDGTA 1518
            |.|||..||..||.:|||||..|  |.|..:....:.:|||:  ||||.|.....|
 Frog   899 VDPKLQSYLSKFKRLEDFRVDPPIAEENGRMTSASNEDPGRR--RHRSGSSKHSPA 952

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
larp	NP_001247347.1	LARP_1_2	730..803	CDD:153403	39/73 (53%)
		DM15	1341..1382	CDD:128927	32/41 (78%)
		DM15	1383..1421	CDD:128927	27/38 (71%)
larp1b	NP_001121461.1	LARP_2	307..379	CDD:153407	39/73 (53%)
		DM15	777..817	CDD:128927	32/40 (80%)
		DM15	818..856	CDD:128927	27/38 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C121183787
eggNOG	1	0.900				E1_COG5193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D258488at2759
OrthoFinder	1	1.000				FOG0001428
OrthoInspector	0	0.000	Not matched by this tool.
Phylome	1	0.910		0.800	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
	6	5.710