Protein Alignment cic and sox19b

DIOPT Version :10

• Sequence 1: NP_001262755.1
• Gene: cic / 53560
• FlyBaseID: FBgn0262582
• Length: 2150
• Species: Drosophila melanogaster
• Sequence 2: NP_571777.1
• Gene: sox19b / 64812
• ZFINID: ZDB-GENE-010111-1
• Length: 293
• Species: Danio rerio
• Alignment Length: 303
• Identity: 69/303 - (22%)
• Similarity: 113/303 - (37%)
• Gaps: 44/303 - (14%)

  Fly  1184 HDDGAAGAPATSAAKRRSQSLSALQQQQQQQQQAGAAGTA---------AGQPANKKIRRPMNAF 1239
            |:...||.|.|            ||............|.|         .|.....|::||||||
Zfish     8 HELKTAGPPHT------------LQHSPGMSPPGSGVGNAHHVSKTACPPGVDPMDKVKRPMNAF 60

  Fly  1240 MIFSKKHRKMVHKKHPNQDNRTVSKILGEWWYALKPEQKAQYHELASSVKDAHFKLHPEWKWCSK 1304
            |::|:..|:.:.:::|...|..:||.||..|..|...:|..:.:.|..::..|.|.:|::|:..:
Zfish    61 MVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLTDVEKRPFIDEAKRLRAVHMKEYPDYKYKPR 125

  Fly  1305 DRRKSSTSTATPGGKASGAAGTGDAKQRLVSVDGSDSLEHDMCPSTPG-GSGSCGGQGISSDLQG 1368
            .:.|:........||...|||...|........||        |...| |.|..||.   ..:||
Zfish   126 RKTKALMKKDNSVGKYPLAAGNLLASAVAQGQGGS--------PRMDGYGWGHAGGY---MGMQG 179

  Fly  1369 DII--PLTIDNYNSTCDEAPTTISMKGNGN--GKLMKNELPSDEDEQMLVVEEEQQQQTVKKIDL 1429
            |.:  |..:..|:.:..:.|.......:.:  .::..:..|......|.:|:.|....:...:..
Zfish   180 DALGYPQQLHRYDLSALQYPAAQPYMNSASSYSQMSYSSSPQQPSPVMSMVKPEPLSHSPTGVPN 244

  Fly  1430 HCRERVNDSDMDDTPFDY---RKQQPEANQRS---AEEHSTSG 1466
            |.|... ..|:.|....|   ......:|||:   .::|...|
Zfish   245 HHRGAF-QGDLRDMISMYIPGGDTSESSNQRAYPGVQQHYLGG 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cic	NP_001262755.1	DUF4819	349..432	CDD:465014
		HMG-box_CIC-like	1231..1308	CDD:438806	24/76 (32%)
sox19b	NP_571777.1	HMG-box_SoxB	51..130	CDD:438790	24/78 (31%)
		SOXp	122..203	CDD:463537	21/91 (23%)