Protein Alignment wun2 and SGPP2

DIOPT Version :10

• Sequence 1: NP_524991.1
• Gene: wun2 / 53558
• FlyBaseID: FBgn0041087
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_689599.2
• Gene: SGPP2 / 130367
• HGNCID: 19953
• Length: 399
• Species: Homo sapiens
• Alignment Length: 176
• Identity: 36/176 - (20%)
• Similarity: 64/176 - (36%)
• Gaps: 43/176 - (24%)

  Fly   178 YHLCHLELPTWLVECY---HRMGIFIFGLGVEQLSTNIAKYSIGRLRPHFYTLCQPVMKDGTTCS 239
            :::..|....|.::.|   ..:.|::..:.:.|::.::.|:.    ||.    ..||:|
Human   101 FYITFLPFTHWNIDPYLSRRLIIIWVLVMYIGQVAKDVLKWP----RPS----SPPVVK------ 151

  Fly   240 DPINAARYIEEFTCAAVDITSKQLKDMRLSFPSGHASFACYSMLYLVIYLHRRMQWKQLRMLCHL 304
               ...|.|.|:                 ..||.||..|......|:|....|.|:..:..|
Human   152 ---LEKRLIAEY-----------------GMPSTHAMAATAIAFTLLISTMDRYQYPFVLGL--- 193

  Fly   305 LQFLLLMFAWYTALTRVSDYKHHWSDVLAGSGIGLTYAVVVTSTMW 350
              .:.::|:....|:|:....|...|||.|..| ....:|:|...|
Human   194 --VMAVVFSTLVCLSRLYTGMHTVLDVLGGVLI-TALLIVLTYPAW 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wun2	NP_524991.1	PAP2_wunen	191..346	CDD:239479	32/157 (20%)
SGPP2	NP_689599.2	PAP2_SPPase1	84..233	CDD:239482	34/171 (20%)
		Phosphatase sequence motif I. /evidence=ECO:0000305	136..144		1/11 (9%)
		Phosphatase sequence motif II. /evidence=ECO:0000305	163..166		2/2 (100%)
		Phosphatase sequence motif III. /evidence=ECO:0000305	206..217		2/10 (20%)