DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-29Ca and SFTPA1

DIOPT Version :9

Sequence 1:	NP_652640.1	Gene:	lectin-29Ca / 53547	FlyBaseID:	FBgn0040098	Length:	236	Species:	Drosophila melanogaster
Sequence 2:	NP_001087239.2	Gene:	SFTPA1 / 653509	HGNCID:	10798	Length:	263	Species:	Homo sapiens

Alignment Length:	171	Identity:	37/171 - (21%)
Similarity:	65/171 - (38%)	Gaps:	35/171 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 NMEQRLEMRLQSFQNQMETKLRALKQQIEPYMENVKMSNKIKMSVFKKIGSRHFYLEKQKKMPWD 135
            ::::.|:..|..|::|:.....||..|           ..| |:|.:|:     :....:.:.:|
Human   117 HLDEELQATLHDFRHQILQTRGALSLQ-----------GSI-MTVGEKV-----FSSNGQSITFD 164

  Fly   136 SAYDTCRQMGGHLANILDEKELNEIFSEETKK--KY-WVDINSRANDGASWISTLSGRDVPFLKW 197
            :..:.|.:.||.:| :....|.||..:...||  .| :|.:....:.|....|  .|..|.:..|
Human   165 AIQEACARAGGRIA-VPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYS--DGTPVNYTNW 226

  Fly   198 -KPNLATNIHNHCVYINSNEMYFE------NCANDNYFACQ 231
             :...|......||     |||.:      ||.......|:
Human   227 YRGEPAGRGKEQCV-----EMYTDGQWNDRNCLYSRLTICE 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-29Ca	NP_652640.1	CLECT	131..231	CDD:153057	25/109 (23%)
SFTPA1	NP_001087239.2	Collagen	43..115	CDD:189968
SFTPA1	NP_001087239.2	CLECT_collectin_like	151..263	CDD:153061	27/125 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000