Protein Alignment SP555 and spsb1

DIOPT Version :10

• Sequence 1: NP_723047.1
• Gene: SP555 / 53471
• FlyBaseID: FBgn0260470
• Length: 301
• Species: Drosophila melanogaster
• Sequence 2: XP_002936603.1
• Gene: spsb1 / 100380153
• XenbaseID: XB-GENE-944621
• Length: 273
• Species: Xenopus tropicalis
• Alignment Length: 285
• Identity: 75/285 - (26%)
• Similarity: 121/285 - (42%)
• Gaps: 73/285 - (25%)

  Fly    33 VTGGLSSGSLDASSSTSPPPR-------FC------------PLPNGVEDNWTWSKRHRSKEVVL 78
            ||||:.  ::|.......|.:       :|            |:.:.|:...:|:...||..|.:
 Frog     5 VTGGIK--TVDMRDPAYRPLKQDLQGLDYCKPARLDLLLDMPPVSHEVQLQHSWNNNDRSLNVFV 67

  Fly    79 RGPNSRTVHFHPNWSKGTAGVQGKRSLNNGRHYWELHVSQRVFGTSIMFGIGTKSARLHANAFRN 143
            :..:....|.|| .::.|..::||.....|.|.||:....|..||..:.|:.|..|.||:..:..
 Frog    68 KEDDKLVFHRHP-VAQSTDAIRGKIGYTRGLHVWEITWVMRQRGTHAVVGVATADAPLHSVGYTT 131

  Fly   144 MLGENEHGWGLS-HKGVLWHEGVALLYTKRFRENQPTQ-----------------IGVLFDGIEG 190
            ::|.|...||.. .:..|:|:|          :|||::                 ..|:.|..:|
 Frog   132 LIGSNGKSWGWDLGRNKLYHDG----------KNQPSRTYPAFLEPDETFIVPDSFLVVLDMDDG 186

  Fly   191 TLTFYKDGKCLGVAFRGLDQIDEPLYPIVCSTAAKTEMTLKCTRREFVN--------LQDRCRAV 247
            ||:|..||:.:|:|||||.  .:.|||:|.:.....|:.::     ::|        |.|.||
 Frog   187 TLSFVVDGQYMGIAFRGLK--GKKLYPVVSAVWGHCEIKMR-----YLNGLDPEPLPLMDLCR-- 242

  Fly   248 IMRRVRSAAQLEKLK----LPLPIA 268
              |.||.|...::|.    ||||.|
 Frog   243 --RSVRLALGKDRLNEIQALPLPAA 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP555	NP_723047.1	SPRY_SOCS3	64..249	CDD:293936	56/210 (27%)
		SOCS	240..273	CDD:470605	14/33 (42%)
spsb1	XP_002936603.1	SPRY_SOCS1-2-4	54..227	CDD:293963	51/190 (27%)
		SOCS_SSB1_4	232..272	CDD:239688	14/38 (37%)