Protein Alignment SF2 and Srsf6

DIOPT Version :10

• Sequence 1: NP_652611.1
• Gene: SF2 / 53443
• FlyBaseID: FBgn0283477
• Length: 255
• Species: Drosophila melanogaster
• Sequence 2: NP_080775.3
• Gene: Srsf6 / 67996
• MGIID: 1915246
• Length: 339
• Species: Mus musculus
• Alignment Length: 286
• Identity: 110/286 - (38%)
• Similarity: 144/286 - (50%)
• Gaps: 57/286 - (19%)

  Fly     8 RIYVGNLPPDIRTKDIQDLFHKFGKVTFVDLKNRRGPPFAFVEFEDARDADDAVKARDGYDYDGY 72
            |:|:|.|..::|.||||..|..:|::..:||||..|    ||||||:|||||||...:..:..|.
Mouse     3 RVYIGRLSYNVREKDIQRFFSGYGRLLEIDLKNGYG----FVEFEDSRDADDAVYELNSKELCGE 63

  Fly    73 RLRVEFPRGGGPGSYRGGNRNDR------SRDGGG-----RMGGR---GPPAKRSQYRVMVTGLP 123
            |:.||..|         |.|.||      ||.|||     |..||   |||. |::||::|..|.
Mouse    64 RVIVEHAR---------GPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPV-RTEYRLIVENLS 118

  Fly   124 ASGSWQDLKDHMREAGDVCFADTYKD--GSGVVEFLRHEDMKYAIKKLDDSRFRSHEGEVAYIRV 186
            :..|||||||.||:||:|.:||.:|:  ..||:||..:.|||.|:.|||.:......     ||:
Mouse   119 SRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRN-----IRL 178

  Fly   187 RED----------SGDNDRGGGGGGSGGGGGGSGGGGSRDY-RDRSRSRSFS---SRPRRRGTPT 237
            .||          ||...|......|......|....||.. :.||||||.|   ||.|.:|..:
Mouse   179 IEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKS 243

  Fly   238 YSPVRRQ--------SYSRSRSRSNY 255
            .|..:.:        |:|||||:..|
Mouse   244 RSKSKSKPKSDRGSHSHSRSRSKDKY 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SF2	NP_652611.1	RRM_SF	3..80	CDD:473069	33/71 (46%)
		RRM2_SRSF1_like	115..188	CDD:410013	32/74 (43%)
Srsf6	NP_080775.3	RRM_SF	1..72	CDD:473069	34/81 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..103		10/27 (37%)
		RRM2_SRSF6	110..182	CDD:410159	33/76 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	176..339		30/94 (32%)