Protein Alignment: RecQ4 and Recql

• Sequence 1: NP_652607.1
• Gene: RecQ4
• FlyBaseID: FBgn0040290
• Length: 1579
• Species: Drosophila melanogaster
• Sequence 2: NP_001342440.1
• Gene: Recql
• MGIID: 103021
• Length: 648
• Species: Mus musculus
• Alignment Length: 705
• Identity: 173/706 (25%)
• Similarity: 294/706 (42%)
• Gaps: 169/706 (24%)

  Fly   782 DFEALDAAVE--ASLSQPVSQEKA--ASPIKTYVGHKIPEEFLKQAGLDTTASSSNRSQHGGVKP 842
            :..|:|..::  ....|.:.|.|:  ...||.|:.....|   ..:.|||:.::.|:...    |
Mouse    17 ELHAIDIQIQELTERRQELLQRKSVLTGKIKQYLEDSSAE---ASSDLDTSPAAWNKEDF----P 74

  Fly   843 LYDLLPDGSVQDTTPEVLEALHMFGHTNFRKGQDRAIMRTLSGLSSLVTLSTGSGKSLCYQLPAY 907
            .:     |.|:|    ||:  ::|....||..|...|..|::.....:.:.||.||||||||||.
Mouse    75 WF-----GKVKD----VLQ--NVFKLQKFRPLQLETINVTMARKDIFLVMPTGGGKSLCYQLPAL 128

  Fly   908 LYSRKVGAITLVISPLVSLMEDQVTGVPHFLRAHCLHTNQTAPQRMK---IQQMIANGEIDILLV 969
            ...    ..||||.||:||||||:..:.....:..:....::.:.:|   .:.:..|.::.::.|
Mouse   129 CSD----GFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSQLKLIYV 189

  Fly   970 SPEAVVAGE-------------RATGFGAILRQLPPIAFACIDEAHCVSQWSHNFRPSYLMICKV 1021
            :||.:...:             |.||             |.:||.||.|||.|:|||.|..: .:
Mouse   190 TPEKIAKSKMFMSRLEKAYEAGRLTG-------------AAVDEVHCCSQWGHDFRPDYKAL-GI 240

  Fly  1022 LRKNLGVRTVLGLTATATLPTRVSIINHLGISDGER--------GIISDIPLPDNLVLSV----S 1074
            |::.....:::|||||||        ||: :.|.::        ...:....| ||...|    |
Mouse   241 LKRQFPNASLMGLTATAT--------NHV-LKDVQKILCVGKCLTFTASFNRP-NLFYEVRQKPS 295

  Fly  1075 KDENRDAALLQLLNSERFEPCQSIIIYCTRRDECERIAGFIRTCVQDRREPTQDQTKKRKRVNWQ 1139
            ..|:....:::|:|. |::. ||.||||..:.:.|:|                  |...:::...
Mouse   296 SAEDFTEDIVKLING-RYKG-QSGIIYCFSQKDSEQI------------------TISLQKLGIH 340

  Fly  1140 AEPYHAGMPASRRRTVQKAFMSNELRIVVATIAFGMGINKPDIRAVIHYNMPRNFESYVQEIGRA 1204
            |..|||.|....:..|...:.:|||::||||:||||||:|||:|.|||::|.::.|:|.||.|||
Mouse   341 AGTYHANMEPEDKTKVHTQWSANELQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRA 405

  Fly  1205 GRDGLPSHCHLFLDAKGGD--------------QSELRRHV-YSNSID---RHVIRKLLQKIFVP 1251
            |||...:.|.|:...  ||              |.:|...| |..::.   |.:|.:...:::..
Mouse   406 GRDDSRADCILYYGF--GDIFRISSMVVMENVGQQKLYEMVSYCQNVSKCRRVLIAQHFDEVWNA 468

  Fly  1252 CSCDKEASK----------------RTALPIPLEGDGPRVHMCPGHEIGFSVEKTVEMLDI---- 1296
            .:|:|....                |..:.|..:.:|....:.|...|...:.|....|.:
Mouse   469 DACNKMCDNCCKDVSFEKKNVTQHCRDLIKILKQAEGLNEKLTPLKLIDAWMGKGAAKLRVAGVV 533

  Fly  1297 ----PAENISTL---------------------LCYMELDPRWCISVLSSAYVMAKVISYGGPKY 1336
                |.|::..:                     :.|:::.||.|: :.:.|:.:...:.......
Mouse   534 APALPREDLERIVAHALLQQYLKEDYSFTAYATISYLKVGPRACL-LSNEAHAVTMQVKKSAQSS 597

  Fly  1337 LKHAAKECPPLAMAIALQIRDKTFKEDSNIIEFSVTDIAAGIGWNSGVVKYQLKD 1391
            ::.|..|...:.     |:..|..::.|...:.|.:.:......|:|..|.:|.|
Mouse   598 VRGALSEARQVE-----QVDSKGEEQSSGNSQKSKSRLQPSGSKNAGAKKRKLDD 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RecQ4	NP_652607.1	RecQ	864..>1218	CDD:223588	119/382 (31%)
		DEAD	872..1039	CDD:278688	56/183 (31%)
		HELICc	1073..1216	CDD:238034	54/147 (37%)
Recql	NP_001342440.1	DEXDc	81..543	CDD:331760	141/518 (27%)
		DEVH box	219..222		2/3 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG0514
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900