Protein Alignment RecQ4 and rcq-5

DIOPT Version :10

• Sequence 1: NP_652607.1
• Gene: RecQ4 / 53438
• FlyBaseID: FBgn0040290
• Length: 1579
• Species: Drosophila melanogaster
• Sequence 2: NP_001309439.1
• Gene: rcq-5 / 175522
• WormBaseID: WBGene00004322
• Length: 821
• Species: Caenorhabditis elegans
• Alignment Length: 902
• Identity: 217/902 - (24%)
• Similarity: 347/902 - (38%)
• Gaps: 287/902 - (31%)

  Fly   756 DDQESSGDEEVQQHPDPNWSS------------------------DEMDVDFEALDAAV------ 790
            ||.:...|:|.......|:::                        .|.:...:.|..|:
 Worm    22 DDSDEETDKEPAAKKPSNYTAWAEIFNKKKTESSAVSAIEKAKKDSEKERQRQKLREAIMERKRR 86

  Fly   791 EASLSQPVSQEKAASPIKTY-----VGHKI---PEEFLKQAGLDTTASSSNR-SQHGGVKPLYDL 846
            ||.:::|..|:  ..|:.|.     |..||   .|:|      |.:..|::| :|...:.| .|.
 Worm    87 EALMNEPKKQK--IEPVSTVKLEKSVNQKISANSEDF------DVSGPSNSRETQESPLDP-NDF 142

  Fly   847 LPDGSVQDTTPEVLEA-----------LHMFGHTNFRKGQDRAIMRTLSGL-----SSLVTLSTG 895
            :.:.....|...::..           |.:|.|..:|   .|..|:.::.:     ...|:|.||
 Worm   143 VANPLAIGTGERLIRGQDIIERRDKVFLELFCHKKYR---SRLQMQAINCILKRKCDVYVSLPTG 204

  Fly   896 SGKSLCYQLPAYLYSRKVGAITLVISPLVSLMEDQVT-----GVPHFLRAHCLHTNQTAPQRMKI 955
            :||||||||||.::    |.||:|||||::||:||::     |:|    ...|::..|..:|.:|
 Worm   205 AGKSLCYQLPAVVH----GGITVVISPLIALMKDQISSLKRKGIP----CETLNSTLTTVERSRI 261

  Fly   956 QQMIANGE--IDILLVSPEAVVA-GERATGFGAILRQLPPIAFACIDEAHCVSQWSHNFRPSYLM 1017
            ...:|..:  |.:|.::.|.|.. |.:....|...|.:  :.:..:||||||:||.|:|||.||.
 Worm   262 MGELAKEKPTIRMLYLTAEGVATDGTKKLLNGLANRDV--LRYIVVDEAHCVTQWGHDFRPDYLT 324

  Fly  1018 ICKVLRKNLGVRTVLGLTATATLPTRVSIINHLGISDGER--------GIISDIPLPDNLVLSVS 1074
            :..:.....||..| .|||||....:..|...|.:.:.|.        .:..|:.:.|:|   .:
 Worm   325 LGSLRDVCPGVPWV-ALTATANAKAQDDIAFQLKLRNPESFKSGTYRDNLFYDVAMRDHL---AT 385

  Fly  1075 KDENRDAALL-------------QLLNSERFEPCQ-------SIIIYCTRRDECERIAGFIRTCV 1119
            ..||..|:.:             .|...|:.|..|       |.|:||..|:||.::|
 Worm   386 APENHMASFITKCLTVDAKTSSSNLTKHEKAERSQNKKTFTGSAIVYCRSRNECGQVA------- 443

  Fly  1120 QDRREPTQDQTKKRKRVNWQAEPYHAGMPASRRRTVQKAFMSNELRIVVATIAFGMGINKPDIRA 1184
                       |..:.....|..||||:....|..||:.:|:||:.:|.||:||||||:|||:||
 Worm   444 -----------KMLEIAGIPAMAYHAGLGKKDRNEVQEKWMNNEIPVVAATVAFGMGIDKPDVRA 497

  Fly  1185 VIHYNMPRNFESYVQEIGRAGRDGLPSHCHLFLDAKGGDQSELRRHVYSNSIDRHVIRKLLQKIF 1249
            |||::..:|...|.||.|||||||..|:|.::...:  |::.|      |.:....:.||.:|
 Worm   498 VIHWSPSQNLAGYYQEAGRAGRDGKRSYCRIYYSKQ--DKNAL------NFLVSGELAKLREK-- 552

  Fly  1250 VPCSCDKEASKRTALPIPLEGDGPRVHMCPGHEIGFSVEKTVEMLDIPAENISTLLCYMELDPRW 1314
                    |.|..|     ||                     |..::..::|.|.|
 Worm   553 --------AKKNNA-----EG---------------------EKAEMQIKSIQTGL--------- 574

  Fly  1315 CISVLSSAYVMAKVISYGGPKYLKHAA-------KECPPLAMAIALQIRDKTFKEDSNIIEFSVT 1372
                       ||::.|......:|.:       .||.| ........||.| |...|:..|..:
 Worm   575 -----------AKMLEYCESARCRHVSIASFFDDTECRP-CKTNCDYCRDPT-KTIRNVEAFINS 626

  Fly  1373 DIAAGIGW-----NSGVVKYQLKDLEWVKVNGYPKRSPITVSFYDLGFRIKVPGDFTESEIDNAL 1432
            :.:.|...     :||             .:|:.       |.|..|.|    |..||.|:.:|.
 Worm   627 EASTGRSMFRKSASSG-------------ESGFD-------SVYGGGKR----GGETEDELLSAA 667

  Fly  1433 DTLYTRSVKQERTQLIQLQYVAHGLAAVAYSSCGQCCNADFPQDRGEQLKAIVRNYFAN-----D 1492
            .|......:.|                               |:..:::::::...||.     .
 Worm   668 STSKDAMDRME-------------------------------QEEAKRVRSVISQEFAKRRQAAP 701

  Fly  1493 YPQDLELEIEPS---NV--PDENIIDDVHALINMYPDNTFTGRNIARIFHGIMSPNY 1544
            .|:.....:||:   ||  |::|:|.:|         ...|..|..|..|..:..|:
 Worm   702 PPRATARRVEPATDVNVIKPEQNVIKNV---------TLETRENWVRFLHRALDSNW 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RecQ4	NP_652607.1	RecQL4_SLD2_NTD	9..55	CDD:412085
		RecQ	855..>1216	CDD:440280	132/412 (32%)
rcq-5	NP_001309439.1	RecQ	182..617	CDD:440280	152/532 (29%)