DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ZFYVE1 and CG31064

DIOPT Version :10

Sequence 1:NP_067083.1 Gene:ZFYVE1 / 53349 HGNCID:13180 Length:777 Species:Homo sapiens
Sequence 2:NP_001287560.1 Gene:CG31064 / 43277 FlyBaseID:FBgn0051064 Length:877 Species:Drosophila melanogaster


Alignment Length:110 Identity:42/110 - (38%)
Similarity:55/110 - (50%) Gaps:15/110 - (13%)


- Green bases have known domain annotations that are detailed below.


Human   550 LKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNKCATSFKDN 614
            ::|.....::||.|   .|||:..:    .:||.|       |..|.|:|....|..|...|...
  Fly   782 MQDQERRQRQLLSG---SAQSLQAM----PEAVGS-------PGIWAPDSIATHCTACEREFNLT 832

Human   615 DTKHHCRACGEGFCDSCSSKTRP-VPERGWGPAPVRVCDNCYEAR 658
            ..|||||:|||.||.:||..|.| :..:|....|||||||||.|:
  Fly   833 RRKHHCRSCGEIFCKACSEHTLPLLNAQGQPGKPVRVCDNCYAAK 877

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZFYVE1NP_067083.1 Bbox1_ZFYVE1_rpt1 16..63 CDD:380877
Bbox1_ZFYVE1_rpt2 69..122 CDD:380878
GBP 174..410 CDD:206650
Required for localization in the lipid droplets. /evidence=ECO:0000269|PubMed:30970241, ECO:0000269|PubMed:31293035 416..777 42/110 (38%)
FYVE_like_SF 594..655 CDD:333710 28/61 (46%)
FYVE_ZFYV1 711..771 CDD:277273
CG31064NP_001287560.1 RUN_RUFY1_like 281..436 CDD:439043
Smc <562..>807 CDD:440809 7/31 (23%)
FYVE_RUFY1_like 813..874 CDD:277261 28/60 (47%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.