Protein Alignment ATP6V1C1 and Atp6v1c1

DIOPT Version :8

• Sequence 1: NP_001686.1
• Gene: ATP6V1C1 / 528
• HGNCID: 856
• Length: 382
• Species: Homo sapiens
• Sequence 2: NP_079770.2
• Gene: Atp6v1c1 / 66335
• MGIID: 1913585
• Length: 382
• Species: Mus musculus
• Alignment Length: 382
• Identity: 375/383 (98%)
• Similarity: 381/383 (99%)
• Gaps: 0/383 (0%)

Human     1 MTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFV 65
            ||||||||||||||||||||||||||:|||||||:||||||||||||||||||||||||||||||
Mouse     1 MTEFWLISAPGEKTCQQTWEKLHAATTKNNNLAVSSKFNIPDLKVGTLDVLVGLSDELAKLDAFV 65

Human    66 EGVVKKVAQYMADVLEDSKDKVQENLLANGVDLVTYITRFQWDMAKYPIKQSLKNISEIIAKGVT 130
            ||||||||||||||||||||||||||||:||||||||||||||||||||||||||||||||||||
Mouse    66 EGVVKKVAQYMADVLEDSKDKVQENLLASGVDLVTYITRFQWDMAKYPIKQSLKNISEIIAKGVT 130

Human   131 QIDNDLKSRASAYNNLKGNLQNLERKNAGSLLTRSLAEIVKKDDFVLDSEYLVTLLVVVPKLNHN 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 QIDNDLKSRASAYNNLKGNLQNLERKNAGSLLTRSLAEIVKKDDFVLDSEYLVTLLVVVPKLNHN 195

Human   196 DWIKQYETLAEMVVPRSSNVLSEDQDSYLCNVTLFRKAVDDFRHKARENKFIVRDFQYNEEEMKA 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   196 DWIKQYETLAEMVVPRSSNVLSEDQDSYLCNVTLFRKAVDDFRHKARENKFIVRDFQYNEEEMKA 260

Human   261 DKEEMNRLSTDKKKQFGPLVRWLKVNFSEAFIAWIHVKALRVFVESVLRYGLPVNFQAMLLQPNK 325
            |||||.||||||||||||||||||||||||||||||:||||||||||||||||||||||||||||
Mouse   261 DKEEMTRLSTDKKKQFGPLVRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAMLLQPNK 325

Human   326 KTLKKLREVLHELYKHLDSSAAAIIDAPMDIPGLNLSQQEYYPYVYYKIDCNLLEFK 382
            |::||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   326 KSVKKLREVLHELYKHLDSSAAAIIDAPMDIPGLNLSQQEYYPYVYYKIDCNLLEFK 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP6V1C1	NP_001686.1	V-ATPase_C	5..370	CDD:308707	358/365 (98%)
		3-helical coiled coil	56..76	CDD:270211	20/20 (100%)
		3-helical coiled coil	121..147	CDD:270211	26/26 (100%)
		3-helical coiled coil	275..306	CDD:270211	30/31 (97%)
Atp6v1c1	NP_079770.2	V-ATPase_C	5..370	CDD:308707	358/365 (98%)
		3-helical coiled coil	56..76	CDD:270211	20/20 (100%)
		3-helical coiled coil	121..147	CDD:270211	26/26 (100%)
		3-helical coiled coil	275..306	CDD:270211	30/31 (97%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C33542190
eggNOG	1	0.900				E1_COG5127
HGNC	1	1.500
Hieranoid	1	1.000
Homologene	1	1.000				H1281
Inparanoid	1	1.050	749	1.000	Inparanoid score	I8436
Isobase	1	0.950		0	Normalized mean entropy	S922
OMA	1	1.010
OrthoDB	1	1.010				D1016088at2759
OrthoFinder	1	1.000				FOG0001431
OrthoInspector	1	1.000				T2453993
orthoMCL	1	0.900				OOG5_127946
Panther	1	1.100			LDO	PTHR10137
Phylome	1	0.910		0.800	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R1630
TreeFam	1	0.960
	16	16.250